ArticleLangmuir : the ACS journal of surfaces and colloids2012
Halothane changes the domain structure of a binary lipid membrane.
Article in Langmuir : the ACS journal of surfaces and colloids, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 29 citations in OpenAlex.
- Anesthetics and Cell-Cell Communication: Potential CaInternational journal of molecular sciences · 2022Review
- Signaling and transport processes related to the carnivorous lifestyle of plants living on nutrient-poor soil.Plant physiology · 2021Review
- Impact of statin intake on malignant hyperthermia: an in vitro and in vivo swine study.BMC anesthesiology · 2020Article
- Review
- Molecular dynamics simulation study of the effect of halothane on mixed DPPC/DPPE phospholipid membranes.Journal of molecular modeling · 2018Article
- The actions of volatile anesthetics: a new perspective.Acta crystallographica. Section D, Structural biology · 2018Review
- Chiral twist drives raft formation and organization in membranes composed of rod-like particles.Proceedings of the National Academy of Sciences of the United States of America · 2017Article
- Alteration of interleaflet coupling due to compounds displaying rapid translocation in lipid membranes.Scientific reports · 2016Article
- Volatile anesthetics inhibit sodium channels without altering bulk lipid bilayer properties.The Journal of general physiology · 2014Article
- Reawakening anaesthesia research.EMBO reports · 2014Article
- Xenon and other volatile anesthetics change domain structure in model lipid raft membranes.The journal of physical chemistry. B · 2013Article
- Exploring volatile general anesthetic binding to a closed membrane-bound bacterial voltage-gated sodium channel via computation.PLoS computational biology · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 4 institutions in 1 country.
Funding
Abstract
X-ray and neutron diffraction studies of a binary lipid membrane demonstrate that halothane at physiological concentrations produces a pronounced redistribution of lipids between domains of different lipid types identified by different lamellar d-spacings and isotope composition. In contrast, dichlorohexafluorocyclobutane (F6), a halogenated nonanesthetic, does not produce such significant effects. These findings demonstrate a specific effect of inhalational anesthetics on mixing phase equilibria of a lipid mixture.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.