ArticleCell stress & chaperones2012
Molecular cloning and characterization of Hsp27.6: the first reported small heat shock protein from Apis cerana cerana.
Article in Cell stress & chaperones, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 65 citations in OpenAlex.
- Article
- Stress in dipteran insects mass-reared for sterile insect technique applications.Insect science · 2025Review
- Identification and expression analysis of heat shock protein family genes of gall fly (Procecidochares utilis) under temperature stress.Cell stress & chaperones · 2023Article
- Impact of phosphorylation of heat shock protein 27 on the expression profile of periodontal ligament fibroblasts during mechanical strain.Journal of orofacial orthopedics = Fortschritte der Kieferorthopadie : Organ/official journal Deutsche Gesellschaft fur Kieferorthopadie · 2023Article
- Identification of Six Small Heat Shock Protein Genes in Ostrinia furnacalis (Lepidoptera: Pyralidae) and Analysis of Their Expression Patterns in Response to Environmental Stressors.Journal of insect science (Online) · 2022Article
- Heat Shock Proteins: Agents of Cancer Development and Therapeutic Targets in Anti-Cancer Therapy.Cells · 2019Review
- Molecular characterization of surface antigen 10 of Eimeria tenella.Parasitology research · 2019Article
- Review
- Identification and Expression Analysis of Four Small Heat Shock Protein Genes in Cigarette Beetle,Insects · 2019Article
- Stress tolerance in diapausing embryos of Artemia franciscana is dependent on heat shock factor 1 (Hsf1).PloS one · 2018Article
- Characteristics and expression of genes encoding two small heat shock protein genes lacking introns from Chilo suppressalis.Cell stress & chaperones · 2018Article
- Identification and expression analysis of multiple small heat shock protein genes in spruce budworm, Choristoneura fumiferana (L.).Cell stress & chaperones · 2018Article
- The Wisdom of Honeybee Defenses Against Environmental Stresses.Frontiers in microbiology · 2018Review
- Environmental Stress Responses ofFrontiers in genetics · 2018Article
- Identification of multiple small heat-shock protein genes in Plutella xylostella (L.) and their expression profiles in response to abiotic stresses.Cell stress & chaperones · 2015Article
- Article
- Characterization and expression of genes encoding three small heat shock proteins in Sesamia inferens (Lepidoptera: Noctuidae).International journal of molecular sciences · 2014Article
- Three Heat Shock Protein Genes from Bactrocera (Tetradacus) minax Enderlein: Gene Cloning, Characterization, and Association with Diapause.Neotropical entomology · 2014Article
- Characterization of the small heat shock protein Hsp27 gene in Chironomus riparius (Diptera) and its expression profile in response to temperature changes and xenobiotic exposures.Cell stress & chaperones · 2014Article
- Five small heat shock protein genes from Chilo suppressalis: characteristics of gene, genomic organization, structural analysis, and transcription profiles.Cell stress & chaperones · 2014Article
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Small heat shock proteins (sHSPs) play an important role in the cellular defense of prokaryotic and eukaryotic organisms against a variety of internal and external stressors. In this study, a cDNA clone encoding a member of the α-crystallin/sHSP family, termed AccHsp27.6, was isolated from Apis cerana cerana. The full-length cDNA is 1,014 bp in length and contains a 708-bp open reading frame encoding a protein of 236 amino acids with a calculated molecular weight of 27.6 kDa and an isoelectric point of 7.53. Seven putative heat shock elements and three NF-κB binding sites were present in the 5'-flanking region, suggesting a possible function in immunity. A semi-quantitative RT-PCR analysis indicated that AccHsp27.6 was expressed in all tested tissues and at different developmental stages. Furthermore, expression of the AccHsp27.6 transcript was induced by exposure to heat shock, H(2)O(2), a number of different chemicals (including SO(2), formaldehyde, alcohol, acetone, chloroform, and the pesticides phoxime and acetamiprid), and the microbes Staphylococcus aureus and Micrococcus luteus. In contrast, the mRNA expression could be repressed by CO(2), the pesticides pyriproxyfen and cyhalothrin, and the microbes Bacillus subtilis and Pseudomonas aeruginosa. Notably, the recombinant AccHsp27.6 protein exhibited significant in vitro molecular chaperone activity and antimicrobial activity. Taken together, these results suggest that AccHsp27.6 might play an important role in the response to abiotic and biotic stresses and in immune reactions.
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