ReviewAdvances in experimental medicine and biology2012
Regulation of the actin cytoskeleton in dendritic spines.
Review in Advances in experimental medicine and biology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
52 citing papers in PubMed, 90 citations in OpenAlex.
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- Partners in plasticity: serotonergic glial interactions in brain circuit remodeling.Frontiers in neuroscience · 2026Review
- The Hippo signaling pathway as a therapeutic target in Alzheimer's disease.Molecular neurodegeneration · 2025Review
- Age-related loss of large dendritic spines in the precuneus is statistically mediated by proteins which are predicted targets of existing drugs.Molecular psychiatry · 2025Article
- Synaptic Plasticity Linked to Ionotropic Glutamate Receptors After Nicotine Exposure.Current neuropharmacology · 2025Review
- H-Ras induces exuberantiScience · 2024Article
- MARCKS and PI(4,5)PMolecular biology of the cell · 2024Article
- Loss of the E3 ubiquitin ligase TRIM67 alters the post-synaptic density proteome.bioRxiv : the preprint server for biology · 2024Article
- Loss of the E3 ubiquitin ligase TRIM67 alters the post-synaptic density proteome.microPublication biology · 2024Article
- Orchestration of synaptic functions by WAVE regulatory complex-mediated actin reorganization.Experimental & molecular medicine · 2023Review
- Steroid Hormone Interaction with Dendritic Spines: Implications for Neuropsychiatric Disease.Advances in neurobiology · 2023Review
- Interactions between the Nicotinic and Endocannabinoid Receptors at the Plasma Membrane.Membranes · 2022Review
- Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.Life science alliance · 2022Article
- Chemical Stimulation of Rodent and Human Cortical Synaptosomes: Implications in Neurodegeneration.Cells · 2021Article
- Three-dimensional real time imaging of amyloid β aggregation on living cells.Scientific reports · 2020Article
- Lanthanum Chloride Impairs Learning and Memory and Induces Dendritic Spine Abnormality by Down-Regulating Rac1/PAK Signaling Pathway in Hippocampus of Offspring Rats.Cellular and molecular neurobiology · 2020Article
- Synaptic actin stabilization protein loss in Down syndrome and Alzheimer disease.Brain pathology (Zurich, Switzerland) · 2020Article
- Tiam1 is Critical for Glutamatergic Synapse Structure and Function in the Hippocampus.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2019Article
- Ghrelin Promotes Cortical Neurites Growth in Late Stage After Oxygen-Glucose Deprivation/Reperfusion Injury.Journal of molecular neuroscience : MN · 2019Article
- How the epigenome integrates information and reshapes the synapse.Nature reviews. Neuroscience · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Spine morphogenesis is largely dependent on the remodeling of the actin cytoskeleton. Actin dynamics within spines is regulated by a complex network of signaling molecules, which relay signals from synaptic receptors, through small GTPases and their regulators, to actin-binding proteins. In this chapter, we will discuss molecules involved in dendritic spine plasticity beginning with actin and moving upstream toward neuromodulators and trophic factors that initiate signaling involved in these plasticity events. We will place special emphasis on small GTPase pathways, as they have an established importance in dendritic spine plasticity and pathology. Finally, we will discuss some epigenetic mechanisms that control spine morphogenesis.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.