ArticleNeuroinformatics2012
neuroVIISAS: approaching multiscale simulation of the rat connectome.
Article in Neuroinformatics, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.
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Who cites it
31 citing papers in PubMed, 1 synthesis or guideline pooled it.
- A systematic review on the quantitative relationship between structural and functional network connectivity strength in mammalian brains.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2019Pooled it
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- Proteomic Characterization of Spinal Cord Myelin in the Mouse.ASN neuro · 2026Article
- Direct comparisons of neural activity during placebo analgesia and nocebo hyperalgesia between humans and rats.Communications biology · 2025Article
- In search of the locus coeruleus: guidelines for identifying anatomical boundaries and electrophysiological properties of the blue spot in mice, fish, finches, and beyond.Journal of neurophysiology · 2024Review
- Cholinergic modulation supports dynamic switching of resting state networks through selective DMN suppression.PLoS computational biology · 2024Article
- Article
- Network models to enhance the translational impact of cross-species studies.Nature reviews. Neuroscience · 2023Review
- Distribution of Cleaved SNAP-25 in the Rat Brain, following Unilateral Injection of Botulinum Neurotoxin-A into the Striatum.International journal of molecular sciences · 2023Article
- Connectomes: from a sparsity of networks to large-scale databases.Frontiers in neuroinformatics · 2023Review
- Reaction-diffusion models in weighted and directed connectomes.PLoS computational biology · 2022Article
- Pathological changes of brain oscillations following ischemic stroke.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2022Review
- The brainstem connectome database.Scientific data · 2022Article
- Olfactory Bulb DToxins · 2022Article
- Distinct structure-function relationships across cortical regions and connectivity scales in the rat brain.Scientific reports · 2020Article
- Mapping the community structure of the rat cerebral cortex with weighted stochastic block modeling.Brain structure & function · 2020Article
- Towards Differential Connectomics with NeuroVIISAS.Neuroinformatics · 2019Article
- Diffusion MRI-based cortical connectome reconstruction: dependency on tractography procedures and neuroanatomical characteristics.Brain structure & function · 2018Article
- A multiscale cerebral neurochemical connectome of the rat brain.PLoS biology · 2017Article
- Prediction of regional functional impairment following experimental stroke via connectome analysis.Scientific reports · 2017Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
neuroVIISAS is a generic platform which allows the integration of neuroontologies, mapping functions for brain atlas development, and connectivity data administration; all of which are required for the analysis of structurally and neurobiologically realistic simulations of networks. What makes neuroVIISAS unique is the ability to integrate neuroontologies, image stacks, mappings, visualizations, analyzes and simulations to use them for modelling and simulations. Based on the analysis of over 2020 tracing studies, atlas terminologies and registered histological stacks of images, neuroVIISAS permits the definition of neurobiologically realistic networks that are transferred to the simulation engine NEST. The analysis on a local and global level, the visualization of connectivity data and the results of simulations offer new possibilities to study structural and functional relationships of neural networks. This paper describes the major components and techniques of how to analyse, visualize and simulate with neuroVIISAS shown on a model network at a coarse CNS level (106 regions, 1566 connections) out of 13681 regions and 134043 connections of the left and right part of the CNS. This network of major components of the left and right hemisphere has small-world properties of the Watts-Strogatz model. Furthermore, synchronized subpopulations, oscillations of rate distributions and a time shift of population activities of the left and right hemisphere were observed in the neurocomputational simulations. In summary, a generic platform has been developed that realizes data-analysis-visualization integration for the exploration of network dynamics on multiple levels.
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22350719What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.