Evidence map›Paper›PMID 22350489›Full record

ReviewTargeted oncology2012

A review on various targeted anticancer therapies.

Junjie Li, Feng Chen, Marlein Miranda Cona, Yuanbo Feng, Uwe Himmelreich, Raymond Oyen, Alfons Verbruggen, Yicheng Ni

Abstract readReview
PubMed Publisher
In one paragraph

Review in Targeted oncology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
7.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it, 72 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Acta pharmaceutica Sinica. B · 2018
    Article
  8. Antitumor Activity of Auger Electron EmitterFrontiers in pharmacology · 2018
    Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Combretastatin A4 phosphate treatment induces vasculogenic mimicry formation of W256 breast carcinoma tumor in vitro and in vivo.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine · 2015
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Research perspectives: gold nanoparticles in cancer theranostics.Quantitative imaging in medicine and surgery · 2013
    Article
  19. Personalized oncology in interventional radiology.Journal of vascular and interventional radiology : JVIR · 2013
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Junjie LiSection of Radiology, Department of Diagnostic Sciences, Faculty of Medicine, University of Leuven, Herestraat 49, BE-3000, Leuven, Belgium.
Feng Chen
Marlein Miranda Cona
Yuanbo Feng
Uwe Himmelreich
Raymond Oyen
Alfons Verbruggen
Yicheng Ni
KU Leuven · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Translational oncology aims to translate laboratory research into new anticancer therapies. Contrary to conventional surgery, chemotherapy, and radiotherapy, targeted anticancer therapy (TAT) refers to systemic administration of drugs with particular mechanisms that specifically act on well-defined targets or biologic pathways that, when activated or inactivated, may cause regression or destruction of the malignant process, meanwhile with minimized adverse effects on healthy tissues. In this article, we intend to first give a brief review on various known TAT approaches that are deemed promising for clinical applications in the current trend of personalized medicine, and then we will introduce our newly developed approach namely small molecular sequential dual targeting theragnostic strategy as a generalized class of TAT for the management of most solid malignancies, which, after optimization, is expected to help improve overall cancer treatability and curability.

Indexed as

AnimalsAntineoplastic AgentsHumansMolecular Targeted TherapyNeoplasmsPrecision MedicineSignal TransductionSmall Molecule LibrariesAntineoplastic AgentsSmall Molecule Libraries

Identifiers

PMID22350489
OpenAlexW1974129739

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.