ArticlePediatric nephrology (Berlin, Germany)2012
Natural history of bilateral mild isolated antenatal hydronephrosis conservatively managed.
Article in Pediatric nephrology (Berlin, Germany), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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16 citing papers in PubMed, 50 citations in OpenAlex.
- The role of antibiotic prophylaxis in mild to moderate isolated hydronephrosis detected in antenatal screening.Investigative and clinical urology · 2020Trial
- Increased kidney length in mild urinary tract dilatation is a significant prognostic factor for non-resolution.Pediatric nephrology (Berlin, Germany) · 2025Article
- Article
- Antenatally detected urinary tract dilatation: long-term outcome.Pediatric nephrology (Berlin, Germany) · 2023Review
- Asymptomatic obstructive hydronephrosis associated with diabetes insipidus: a case report and review.Translational pediatrics · 2021Article
- Appropriate timing of performing abdominal ultrasonography and termination of follow-up observation for antenatal grade 1 or 2 hydronephrosis.BMC urology · 2020Article
- Antenatally detected urinary tract dilatation: a 12-15-year follow-up.Pediatric nephrology (Berlin, Germany) · 2020Article
- Evaluation of Congenital Hydronephrosis with Static and Dynamic Magnetic Resonance Urography in Comparation to Dynamic Renal Scintigraphy.Acta informatica medica : AIM : journal of the Society for Medical Informatics of Bosnia & Herzegovina : casopis Drustva za medicinsku informatiku BiH · 2019Article
- Time to resolution of isolated antenatal hydronephrosis with anteroposterior diameter ≤ 20 mm.European journal of pediatrics · 2019Article
- Comparison Characteristics of Family and Demographic of Children with Antenatal Hydronephrosis between 2Iranian journal of public health · 2018Article
- Prenatal natural history of isolated fetal mild bilateral pyelectasis.Clinics (Sao Paulo, Brazil) · 2016Article
- Postnatal Evaluation and Outcome of Prenatal Hydronephrosis.Iranian journal of pediatrics · 2016Article
- Resolution rate of isolated low-grade hydronephrosis diagnosed within the first year of life.Journal of pediatric urology · 2014Article
- Outcome of vesicoureteral reflux in infants: impact of prenatal diagnosis.Iranian journal of pediatrics · 2013Article
- Revised guidelines on management of antenatal hydronephrosis.Indian journal of nephrology · 2013Article
- Congenital giant hydronephrosis: a rare cause for upper abdominal mass in the newborn.Journal of clinical neonatology · 2013Article
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2 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundThe purpose of this study was to assess the prevalence and outcome of newborns with bilateral mild isolated antenatal hydronephrosis managed with neither antibiotic prophylaxis nor voiding cystourethrography (VCUG).
methodsInclusion criteria were ultrasonographic evidence of an anterior-posterior pelvic diameter (APPD) of 5-15 mm at the third trimester of gestation and on the first postnatal ultrasound sonogram. Exclusion criteria were an APPD >15 mm, calyectasis, hydroureteronephrosis, or renal or bladder abnormalities. Ultrasound follow-up was performed. Parents were familiarized with the signs of urinary tract infection (UTI). If UTI was confirmed, VCUG was performed. The outcome was assessed as intrauterine resolution of hydronephrosis, total or partial resolution, stability, or progression.
resultsHydronephrosis was bilateral in 98 of the 236 newborns (196 hydronephrotic kidneys) with mild isolated antenatal hydronephrosis enrolled in this study. Nine patients had UTI, and none showed reflux. After a mean follow-up of 15 months, 74 kidneys showed intrauterine resolution (38%), 82 (42%) showed total resolution, 13 showed partial resolution, 24 were stable, and 3 showed progression. Bilateral cases represented 42% of mild isolated antenatal hydronephrosis. During the first year of life, 80% of the kidneys showed total hydronephrosis resolution, 9% of patients had UTI, and none of the patients showed reflux.
conclusionsAntibiotic prophylaxis and VCUG are not mandatory in newborns with bilateral mild isolated antenatal hydronephrosis, but clinical and ultrasound follow-up are recommended during the first year of life.
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