ArticleInternational archives of occupational and environmental health2013
Pneumoproteins in sewage workers exposed to sewage dust.
Article in International archives of occupational and environmental health, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.
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Who cites it
13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 29 citations in OpenAlex.
- Global systematic review of occupational health and safety outcomes among sanitation and hygiene workers.Frontiers in public health · 2023Pooled it
- Systematic Review of Potential Occupational Respiratory Hazards Exposure Among Sewage Workers.Frontiers in public health · 2021Pooled it
- Endotoxins and Biological Implications-Review.Public health challenges · 2026Review
- TLR/NF-κB activation in vitro as a tool in the assessment of occupational bioaerosol exposure and health risks in wastewater treatment plants.Journal of exposure science & environmental epidemiology · 2026Article
- Immunotoxicity of Inhalable Organic Dust Samples Based on In Vitro Analysis of Human Respiratory Epithelial Cells.International journal of molecular sciences · 2026Article
- From respiratory infections to environmental exposures: CC16 is a key modulator of airway homeostasis.Frontiers in medicine · 2026Review
- Occupational health of drilling waste workers as related to microbial exposure and waste treatment methods.Annals of work exposures and health · 2025Article
- Health Outcomes Related to Multiple Exposures in Occupational Settings: A Review.Safety and health at work · 2024Review
- Characteristics and Determinants of the Presence of Respiratory Symptoms among Sewage Workers in Malaysia.Journal of environmental and public health · 2022Article
- Naphthalene: irritative and inflammatory effects on the airways.International archives of occupational and environmental health · 2021Article
- Respiratory health and inflammatory markers - Exposure to respirable dust and quartz and chemical binders in Swedish iron foundries.PloS one · 2019Article
- Biomarkers of inflammation in workers exposed to compost and sewage dust.International archives of occupational and environmental health · 2016Article
- Indoor and outdoor exposure to ultrafine, fine and microbiologically derived particulate matter related to cardiovascular and respiratory effects in a panel of elderly urban citizens.International journal of environmental research and public health · 2015Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe association between exposure to bacteria and endotoxins in sewage dust and the serum concentrations of pneumoproteins in sewage treatment plant workers were studied.
methodsForty-four workers from eight sewage treatment plants and 38 reference workers participated in the study. Microbial aerosol was collected by personal inhalable samplers. The concentrations of bacteria and endotoxins were determined by fluorescence microscopy and the Limulus assay, respectively. Pneumoproteins (Clara cell protein: CC16, and Surfactant proteins A and D: SP-A, SP-D) were determined by ELISA in blood samples collected post-shift.
resultsThe exposure to dust ranged from 0.02 to 9.3 (geometric mean (GM) 0.3 mg/m(3), of bacteria from 0.3 to 4,900 × 10(3) (GM 27 × 10(3)) cells/m(3) and endotoxins from 1 to 3,160 (GM 28) EU/m(3). The exposed workers had lower CC16 [arithmetic mean (AM) 4.9 ng/ml] compared to the referents (AM 6.4 ng/ml, p < 0.01). No significant difference was observed for SP-D and SP-A. Exposure to bacteria was positively associated with CC16 (p < 0.05) and SP-D (p < 0.05), adjusting for possible confounders.
conclusionsThis study showed that exposed workers had lower serum concentration of CC16 as compared to the referents, which may reflect a long-term effect on secretion of these pneumoproteins. The positive association between exposure to bacteria and the serum concentrations of CC16 and SP-D may be explained by a transient increased permeability of the lung-blood barrier.
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