SynthesisSurgical endoscopy2012
Open versus laparoscopic pyloromyotomy for hypertrophic pyloric stenosis: a systematic review and meta-analysis focusing on major complications.
Synthesis in Surgical endoscopy, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 4 syntheses or guidelines pooled it, 103 citations in OpenAlex.
- Open versus laparoscopic pyloromyotomy for pyloric stenosis.The Cochrane database of systematic reviews · 2021Pooled it
- Single-port laparoscopic appendicectomy versus conventional three-port approach for acute appendicitis in children: a systematic review and meta-analysis.Pediatric surgery international · 2021Pooled it
- Laparoscopic versus open pyloromyotomy in infants: a systematic review and meta-analysis.Pediatric surgery international · 2017Pooled it
- A systematic review of the quality of conduct and reporting of systematic reviews and meta-analyses in paediatric surgery.PloS one · 2017Pooled it
- Standardized laparoscopic pyloromyotomy may reduce the impact of surgeon experience: a comparative study.Surgery today · 2026Article
- Diagnostic Accuracy of Acid-Base Status in Infants with Hypertrophic Pyloric Stenosis.Children (Basel, Switzerland) · 2022Article
- Transumbilical single-site two incision laparoscopic pyloromyotomy for pediatric hypertrophic pyloric stenosis.BMC surgery · 2022Article
- The Safety and Effectiveness of Laparoscopic Pyloromyotomy Using 3-mm Electrocautery Hook versus Open Surgery for Treatment of Hypertrophic Pyloric Stenosis in Infants.Children (Basel, Switzerland) · 2021Article
- Laparoscopic vs. Open Pyloromyotomy in Treatment of Infantile Hypertrophic Pyloric Stenosis.Frontiers in pediatrics · 2020Article
- Letter to the Editor: "Gastric Per Oral Endoscopic Myotomy (G-POEM) for the Treatment of Refractory Gastroparesis: Early Experience".Digestive diseases and sciences · 2019Article
- Developmental outcome at 3 years of age of infants following surgery for infantile hypertrophic pyloric stenosis.Pediatric surgery international · 2019Article
- Idiopathic Hypertrophic Pyloric Stenosis with Complete Ladd's Band: A Rare Association.European journal of pediatric surgery reports · 2019Article
- Antibiotic Prophylaxis for Pyloromyotomy in Children: An Opportunity for Better Stewardship.World journal of surgery · 2018Article
- Trends and surgical outcomes of laparoscopic versus open pyloromyotomy.Surgical endoscopy · 2018Article
- Pyloric stenosis: an enigma more than a century after the first successful treatment.Pediatric surgery international · 2018Review
- Differential learning processes for laparoscopic and open supraumbilical pyloromyotomy.Pediatric surgery international · 2016Article
- Laparoscopic pyloromyotomy: Lessons learnt in our first 101 cases.Journal of Indian Association of Pediatric Surgeons · 2014Article
- Laparoscopic pyloromyotomy, the tail of the learning curve.Surgical endoscopy · 2013Article
- A novel two-port single-site laparoscopic pyloromyotomy for infantile hypertrophic pyloric stenosis.Journal of minimal access surgeryArticle
- Centennial of pyloromyotomy.Journal of neonatal surgeryArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThere is an ongoing debate about whether laparoscopic pyloromyotomy (LP) or open pyloromyotomy (OP) is the best option for treating hypertrophic pyloric stenosis (HPS). The aim of this study was to compare the results of both surgical strategies by means of a systematic review and meta-analysis of the available literature.
methodsA systematic search for randomized clinical trials (RCTs) comparing OP and LP was conducted. Studies were reviewed independently for quality, inclusion and exclusion criteria, and outcomes. Primary outcome was major postoperative complications (i.e., incomplete pyloromyotomy, perforation, and need for reoperation). Secondary outcomes were time to full feed, postoperative hospital stay, and any other postoperative complications.
resultsFour RCTs with a total of 502 patients (OP 255, LP 247) fulfilled the inclusion criteria and were analyzed in this review. These trials showed an absolute incidence of major postoperative complications of 4.9% in the LP group. Meta-analysis showed that LP did not lead to significantly more major postoperative complications (ARR 3%, 95% CI -3 to 8%) than OP. The mean difference in time to full feed was significant (2.27 h, 95% CI -4.26 to -0.29 h) and the mean difference in postoperative hospital stay tended to be shorter (2.41 h, 95% CI -6.10 to 1.28 h), both in favor of LP.
conclusionSo far, the major postoperative complication rate after LP for HPS is not substantially higher than after OP. Because time to full feed and postoperative hospital stay are at best a few hours shorter after LP than after OP, the laparoscopic technique might be acknowledged as the standard of care if the major postoperative complication rate is low. Hence, this laparoscopic procedure should preferably be performed in centers with pediatric surgeons with expertise in this procedure.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.