ArticleJournal of neurology2012
Nociceptive pathway function is normal in cervical dystonia: a study using laser-evoked potentials.
Article in Journal of neurology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 25 citations in OpenAlex.
- Pain characteristics in isolated cervical dystonia: comparison to orthopedic cervical conditions and assessment of botulinum toxin effects.Journal of neural transmission (Vienna, Austria : 1996) · 2026Article
- Multicenter validation of the Italian Pain in Dystonia Scale in idiopathic adult-onset cervical dystonia.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026Article
- The Second Hit Hypothesis in Animal and Human Dystonia: The Role of Peripheral Nerve Trauma and Spinal Cord Injury.Movement disorders : official journal of the Movement Disorder Society · 2026Review
- Documented pain phenotypes and interventional pain-care exposure in patients with dystonia: a retrospective text-mining cohort study.Clinical parkinsonism & related disorders · 2026Article
- Pain control due to botulinum toxin therapy in cervical dystonia relates to the sensorimotor integration process.Dystonia (Lausanne, Switzerland) · 2023Article
- Non-motor phenotypic subgroups in adult-onset idiopathic, isolated, focal cervical dystonia.Brain and behavior · 2021Article
- Abnormal regional homogeneity and its relationship with symptom severity in cervical dystonia: a rest state fMRI study.BMC neurology · 2021Article
- The Use of Botulinum Toxin for Treatment of the Dystonias.Handbook of experimental pharmacology · 2021Article
- Advances in the pathophysiology of adult-onset focal dystonias: recent neurophysiological and neuroimaging evidence.F1000Research · 2020Review
- The role of sensory information in the pathophysiology of focal dystonias.Nature reviews. Neurology · 2019Review
- Pain in Neurodegenerative Disease: Current Knowledge and Future Perspectives.Behavioural neurology · 2016Review
Corrections and comments
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Authors and funding
7 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cervical dystonia (CD) is often associated with pain in the neck muscles, though the mechanisms underlying pain in this condition are still largely unknown. The aim of this study was to assess laser pain rating and CO(2) laser-evoked potentials (LEPs) in CD patients with pain in the posterior neck region. We assessed the N2/P2 LEP complex and laser pain rating in a group of 20 CD patients and in 21 normal subjects. In 11 of the 20 CD patients (group I), the N2/P2 complex was recorded after stimulation of the skin overlying the right and left deltoid muscles (painless and non-dystonic). In the remaining nine CD patients (group II), the N2/P2 complex was recorded after stimulation of the skin over the splenius capitis muscle (painful and dystonic) and after stimulation of the skin overlying the contralateral splenius muscle (painless and non-dystonic). In group I patients, the N2/P2 LEP amplitude and laser pain rating after stimulation of both shoulders did not differ significantly from those obtained in normal subjects. Similarly, in group II patients, the N2/P2 LEP amplitude and laser pain rating after stimulation of the painful and dystonic splenius capitis muscle did not differ significantly from those obtained from either the contralateral painless, non-dystonic splenius capitis or normal subjects. The results of this study demonstrate that cutaneous nociceptive pathway function in CD patients is normal, thereby indicating that muscle pain in CD is not associated with any central sensitization of nociceptive inputs in either painful (dystonic) or non-painful (non-dystonic) body areas.
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