Evidence map›Paper›PMID 22349564›Full record

ArticleMitochondrion2012

Schizosaccharomyces pombe homologs of the Saccharomyces cerevisiae mitochondrial proteins Cbp6 and Mss51 function at a post-translational step of respiratory complex biogenesis.

Inge Kühl, Thomas D Fox, Nathalie Bonnefoy

Open access · greenAbstract read
In one paragraph

Article in Mitochondrion, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
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  4. AEMBO reports · 2017
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Inge KühlCentre de Génétique Moléculaire du CNRS, UPR 3404, FRC3115, Avenue de la Terrasse, 91198 Gif-sur-Yvette Cedex, France.
Thomas D Fox
Nathalie Bonnefoy
Centre National de la Recherche Scientifique · FRCornell University · US

Funding

TRANSLATIONAL CONTROL OF YEAST MITOCHONDRIAL GENESR01GM029362 · NIGMS · CORNELL UNIVERSITY ITHACA · PI FOX, THOMAS DAVID · 1985 to 2013
$6.1M
NIGMS NIH HHS GM29362NIGMS NIH HHS R01 GM029362
6 · The paper itself

Abstract

Complexes III and IV of the mitochondrial respiratory chain contain a few key subunits encoded by the mitochondrial genome. In Saccharomyces cerevisiae, fifteen mRNA-specific translational activators control mitochondrial translation, of which five are conserved in Schizosaccharomyces pombe. These include homologs of Cbp3, Cbp6 and Mss51 that participate in translation and the post-translational steps leading to the assembly of respiratory complexes III and IV. In this study we show that in contrast to budding yeast, Cbp3, Cbp6 and Mss51 from S. pombe are not required for the translation of mitochondrial mRNAs, but fulfill post-translational functions, thus probably accounting for their conservation.

Indexed as

Protein BiosynthesisSequence Homology, Amino AcidAmino Acid SequenceElectron Transport Complex IVFungal ProteinsGene Expression Regulation, FungalMitochondriaMitochondrial ProteinsMolecular Sequence DataOrganelle BiogenesisRNA, MessengerRNA, MitochondrialSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsSchizosaccharomycesTranscription FactorsCbp6 protein, S cerevisiaeElectron Transport Complex IVFungal Proteinsmitochondrial messenger RNAMitochondrial ProteinsMss51 protein, S cerevisiaeRNA, MessengerRNA, MitochondrialSaccharomyces cerevisiae ProteinsTranscription Factors

Identifiers

PMID22349564
PMCPMC3361529
OpenAlexW2063436194

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.