ArticleDie Naturwissenschaften2012
On dating stages in prebiotic chemical evolution.
Article in Die Naturwissenschaften, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
6 citing papers in PubMed.
- From rule-taking to rule-making chemistry: a minimal population-environment feedback model.Journal of the Royal Society, Interface · 2026Article
- Determination of the Amino Acid Recruitment Order in Early Life by Genome-Wide Analysis of Amino Acid Usage Bias.Biomolecules · 2022Article
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- Article
- 227 Views of RNA: Is RNA Unique in Its Chemical Isomer Space?Astrobiology · 2015Article
- Uniquely localized intra-molecular amino acid concentrations at the glycolytic enzyme catalytic/active centers of Archaea, Bacteria and Eukaryota are associated with their proposed temporal appearances on earth.Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life · 2013Article
Corrections and comments
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Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The notion that RNA must have had a unique and decisive role in the development of life needs hardly be questioned. However, the chemical complexity and other properties of RNA, such as high solubility in water and vulnerability to degradation, make it improbable that RNA could have had an early presence in the development of life on Earth or on any comparable telluric planet. Rather, the task of origin of life research must surely be to identify those chemical processes which could have taken place on Earth that could accumulate the complexity and rich molecular information content needed to sustain primitive life, and ultimately give rise to RNA. A collection of likely chemical precursors to modern biomolecules is listed here together with calculations of their molecular complexity. These complexity scores are then used to propose an ordering, on a timescale, of when they might have appeared on Earth. These pre-RNA living systems would have flourished during the first ~0.3 Gyrs after the start of the Archaean era (~4.2 Gyr ago). If there ever was an "RNA-world" it could have started after that initial period (~3.9 Gyrs ago), later to be complemented with the appearance of duplex DNA at about ~3.6 Gyrs ago, some time before the earliest known stromatolites (~3.4 Gyr).
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.