Evidence map›Paper›PMID 22349211›Full record

ReviewCellular and molecular life sciences : CMLS2012

Cytoskeleton responses in wound repair.

Maria Teresa Abreu-Blanco, James J Watts, Jeffrey M Verboon, Susan M Parkhurst

Abstract readReview
In one paragraph

Review in Cellular and molecular life sciences : CMLS, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers.

0numbers the graph read from it
0cells of the map it votes in
63citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

63 citing papers in PubMed.

  1. Article
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  8. Review
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  11. Article
  12. Therapeutic TNF Inhibitors Exhibit Differential Levels of Efficacy in Accelerating Cutaneous Wound Healing.JID innovations : skin science from molecules to population health · 2024
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Engineered combinatorial cell device for wound healing and bone regeneration.Frontiers in bioengineering and biotechnology · 2023
    Article
  18. Aerobic glycolysis is important for zebrafish larval wound closure and tail regeneration.Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society · 2022
    Article
  19. Pyroptosis and pyroptosis-inducing cancer drugs.Acta pharmacologica Sinica · 2022
    Review
  20. Wound Healing from an Actin Cytoskeletal Perspective.Cold Spring Harbor perspectives in biology · 2022
    Review

3 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Maria Teresa Abreu-BlancoDivision of Basic Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109-1024, USA.
James J Watts
Jeffrey M Verboon
Susan M Parkhurst

Funding

Translational Bioimaging Core Shared ResourceP30CA015704 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI Eric Collisson · 1985 to 2026
$296.4M
Molecular and Cellular Mechanisms of Wound Repair and MorphogenesisR01GM092731 · NIGMS · FRED HUTCHINSON CANCER RESEARCH CENTER · PI PARKHURST, SUSAN M · 2010 to 2013
$1.7M
NCI NIH HHS P30 CA015704NIGMS NIH HHS GM092731NIGMS NIH HHS R01 GM092731
6 · The paper itself

Abstract

Wound repair on the cellular and multicellular levels is essential to the survival of complex organisms. In order to avoid further damage, prevent infection, and restore normal function, cells and tissues must rapidly seal and remodel the wounded area. The cytoskeleton is an important component of wound repair in that it is needed for actomyosin contraction, recruitment of repair machineries, and cell migration. Recent use of model systems and high-resolution microscopy has provided new insight into molecular aspects of the cytoskeletal response during wound repair. Here we discuss the role of the cytoskeleton in single-cell, embryonic, and adult repair, as well as the striking resemblance of these processes to normal developmental events and many diseases.

Indexed as

ActomyosinAnimalsCadherinsCalcium SignalingCell MembraneCytoskeletal ProteinsCytoskeletonEmbryo, MammalianEmbryo, NonmammalianHumansModels, BiologicalMorphogenesisPrenatal InjuriesWound HealingActomyosinCadherinsCytoskeletal Proteins

Identifiers

PMID22349211
PMCPMC3388155

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.