Evidence map›Paper›PMID 22348705›Full record

ReviewGenome biology2012

The genetic basis of alcoholism: multiple phenotypes, many genes, complex networks.

Tatiana V Morozova, David Goldman, Trudy F C Mackay, Robert R H Anholt

Abstract readReview
In one paragraph

Review in Genome biology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Change in brain molecular landscapes following electrical stimulation of the nucleus accumbens.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Hazardous drinking and alcohol use disorders.Nature reviews. Disease primers · 2022
    Review
  8. Article
  9. Article
  10. Article
  11. Protein Tyrosine Phosphatase β/ζ and Alcohol Use Disorder: A Commentary.Alcoholism, clinical and experimental research · 2020
    Article
  12. Closing the 'phenotype gap' in precision medicine: improving what we measure to understand complex disease mechanisms.Mammalian genome : official journal of the International Mammalian Genome Society · 2019
    Review
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Tatiana V MorozovaDepartment of Biology, Box 7617, North Carolina State University, Raleigh, NC 27695, USA.
David Goldman
Trudy F C Mackay
Robert R H Anholt

Funding

Integrative genetics of behavior with high throughput technologiesZIAAA000301 · NIAAA · NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM · PI GOLDMAN, DAVID · 2009 to 2025
$68.6M
QUANTITATIVE TRAIT LOCI IN DROSOPHILAR01GM045146 · NIGMS · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI ANHOLT, ROBERT R. H, MACKAY, TRUDY F. · 1991 to 2012
$5.1M
NIAAA NIH HHS AA016569
6 · The paper itself

Abstract

Alcoholism is a significant public health problem. A picture of the genetic architecture underlying alcohol-related phenotypes is emerging from genome-wide association studies and work on genetically tractable model organisms.

Indexed as

AlcoholismAnimalsDisease Models, AnimalDrosophilaEthanolGenetic Predisposition to DiseaseGenome-Wide Association StudyHumansMalate DehydrogenaseMicePhenotypeQuantitative Trait LociEthanolMalate Dehydrogenase

Identifiers

PMID22348705
PMCPMC3334563

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.