Evidence map›Paper›PMID 22348650›Full record

Trial reportPsychological medicine2012

Internet-based cognitive behaviour therapy for obsessive-compulsive disorder: a randomized controlled trial.

E Andersson, J Enander, P Andrén, E Hedman, B Ljótsson, T Hursti, J Bergström, V Kaldo, N Lindefors, G Andersson and 1 more

3 registry-linked trialsAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Psychological medicine, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 87 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
87citing papers in PubMed, 7 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01347099 phase2completednot on this map

Internet-based Cognitive Behavior Therapy for Obsessive Compulsive Disorder: A Randomized Controlled Trial

TypeinterventionalSponsorKarolinska InstitutetRan2011 to 2011Enrolled101ConditionsObsessive Compulsive DisorderArmsInternet-based cognitive behavior therapy, Support therapy on Internet
NCT04386291 nacompletednot on this mapstarted 2020, after this paper: background citation

Meditation and Yoga for Heightened Anxiety Related to COVID-19

TypeinterventionalSponsorResearch Foundation for Mental Hygiene, Inc.Ran2020 to 2022Enrolled256ConditionsGeneralized Anxiety, Health AnxietyArmsAnxiety Reduction Training, Kundalini Yoga and Anxiety Reduction Training, Meditation and Anxiety Reduction Training
NCT06658756 nanot yet recruitingnot on this mapstarted 2025, after this paper: background citation

Implementation of Internet-Based Psychotherapy for Obsessive-Compulsive Disorder (OCD) in Primary Health Care in Two Cities in the State of São Paulo

TypeinterventionalSponsorUniversity of Sao Paulo General HospitalRan2025 to 2028Enrolled140ConditionsObsessive-Compulsive DisorderArmsinternet-CBT
3 · Its place in the literature

Who cites it

87 citing papers in PubMed, 7 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Pooled it
  7. Pooled it
  8. Trial
  9. Trial
  10. Trial
  11. Trial
  12. Trial
  13. Trial
  14. Trial
  15. Trial
  16. Trial
  17. Trial
  18. Trial
  19. Trial
  20. Trial

27 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

E AnderssonDepartment of Clinical Neuroscience, Division of Psychiatry, Karolinska Institutet, Stockholm, Sweden. erik.m.andersson@ki.se
J Enander
P Andrén
E Hedman
B Ljótsson
T Hursti
J Bergström
V Kaldo
N Lindefors
G Andersson
C Rück

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCognitive behaviour therapy (CBT) is an effective treatment for obsessive-compulsive disorder (OCD) but access to CBT is limited. Internet-based CBT (ICBT) with therapist support is potentially a more accessible treatment. There are no randomized controlled trials testing ICBT for OCD. The aim of this study was to investigate the efficacy of ICBT for OCD in a randomized controlled trial.

methodParticipants (n=101) diagnosed with OCD were randomized to either 10 weeks of ICBT or to an attention control condition, consisting of online supportive therapy. The primary outcome measure was the Yale-Brown Obsessive Compulsive Scale (YBOCS) administered by blinded assessors.

resultsBoth treatments lead to significant improvements in OCD symptoms, but ICBT resulted in larger improvements than the control condition on the YBOCS, with a significant between-group effect size (Cohen's d) of 1.12 (95% CI 0.69-1.53) at post-treatment. The proportion of participants showing clinically significant improvement was 60% (95% CI 46-72) in the ICBT group compared to 6% (95% CI 1-17) in the control condition. The results were sustained at follow-up.

conclusionsICBT is an efficacious treatment for OCD that could substantially increase access to CBT for OCD patients. Replication studies are warranted.

Indexed as

InternetAdolescentAdultAgedCognitive Behavioral TherapyFemaleFollow-Up StudiesHumansMaleMiddle AgedObserver VariationObsessive-Compulsive DisorderPsychiatric Status Rating ScalesSwedenTherapy, Computer-AssistedTreatment Outcome

Identifiers

PMID22348650
PMCPMC3435873

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.