SynthesisPloS one2012
Epidemiological evidence for work load as a risk factor for osteoarthritis of the hip: a systematic review.
Synthesis in PloS one, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 9 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
38 citing papers in PubMed, 9 syntheses or guidelines pooled it, 90 citations in OpenAlex.
- Hip osteoarthritis and occupational mechanical exposures: a systematic review and meta-analysis.Scandinavian journal of work, environment & health · 2024Pooled it
- Work-relatedness of lateral epicondylitis: Systematic review including meta-analysis and GRADE work-relatedness of lateral epicondylitis.American journal of industrial medicine · 2022Pooled it
- Men and Women's Occupational Activities and the Risk of Developing Osteoarthritis of the Knee, Hip, or Hands: A Systematic Review and Recommendations for Future Research.Arthritis care & research · 2020Pooled it
- Risk factors for development of lower limb osteoarthritis in physically demanding occupations: A narrative umbrella review.Journal of occupational health · 2020Pooled it
- Exposure-Response Relationship and Doubling Risk Doses-A Systematic Review of Occupational Workload and Osteoarthritis of the Hip.International journal of environmental research and public health · 2019Pooled it
- Hip Osteoarthritis and Physical Workload: Influence of Study Quality on Risk Estimations-A Meta-Analysis of Epidemiological Findings.International journal of environmental research and public health · 2019Pooled it
- Quantitative Measures of Physical Risk Factors Associated with Work-Related Musculoskeletal Disorders of the Elbow: A Systematic Review.International journal of environmental research and public health · 2019Pooled it
- Dose-response relationship between cumulative physical workload and osteoarthritis of the hip - a meta-analysis applying an external reference population for exposure assignment.BMC musculoskeletal disorders · 2018Pooled it
- Occupational Strain as a Risk for Hip Osteoarthritis.Deutsches Arzteblatt international · 2017Pooled it
- Pelvic osteotomies for acetabular dysplasia: development and current concepts in Japan.International orthopaedics · 2026Review
- Hip Osteoarthritis and the Human Microbiome: Current Concepts, Biological Insights and Future Directions.Orthopedic reviews · 2026Article
- The gut microbiome and osteoarthritis.Reumatologia · 2025Review
- Article
- Physically demanding occupations among females and sex-related differences to develop osteoarthritis of the hip: a systematic review and meta-analysis.Journal of occupational medicine and toxicology (London, England) · 2024Article
- Risk of symptomatic osteoarthritis associated with exposure to ergonomic factors at work in a nationwide Italian survey.International archives of occupational and environmental health · 2023Article
- Influence of physically demanding occupations on the development of osteoarthritis of the hip: a systematic review.Journal of occupational medicine and toxicology (London, England) · 2022Review
- Highlighting the Benefits of Rehabilitation Treatments in Hip Osteoarthritis.Medicina (Kaunas, Lithuania) · 2022Observational
- Appropriateness of hip osteoarthritis management in clinical practice compared with the American Academy of Orthopaedic Surgeons (AAOS) criteria.International orthopaedics · 2021Article
- Lifetime occupation is not associated with radiographic osteoarthritis of the first metatarsophalangeal joint in a cohort study of UK women.Journal of foot and ankle research · 2020Article
- Pathogenesis of Osteoarthritis: Risk Factors, Regulatory Pathways in Chondrocytes, and Experimental Models.Biology · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveOsteoarthritis of the hip (OA) is a common degenerative disorder of the joint cartilage that presents a major public health problem worldwide. While intrinsic risk factors (e.g, body mass and morphology) have been identified, external risk factors are not well understood. In this systematic review, the evidence for workload as a risk factor for hip OA is summarized and used to derive recommendations for prevention and further research.
methodsEpidemiological studies on workload or occupation and osteoarthritis of the hip were identified through database and bibliography searches. Using pre-defined quality criteria, 30 studies were selected for critical evaluation; six of these provided quantitative exposure data.
resultsStudy results were too heterogeneous to develop pooled risk estimates by specific work activities. The weight of evidence favors a graded association between long-term exposure to heavy lifting and risk of hip OA. Long-term exposure to standing at work might also increase the risk of hip OA.
conclusionsIt is not possible to estimate a quantitative dose-response relationship between workload and hip OA using existing data, but there is enough evidence available to identify job-related heavy lifting and standing as hazards, and thus to begin developing recommendations for preventing hip OA by limiting the amount and duration of these activities. Future research to identify specific risk factors for work-related hip OA should focus on implementing rigorous study methods with quantitative exposure measures and objective diagnostic criteria.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.