ArticlePatient preference and adherence2012
Impact of pharmacist interventions on patients' adherence to antidepressants and patient-reported outcomes: a systematic review.
Article in Patient preference and adherence, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed, 1 synthesis or guideline pooled it, 78 citations in OpenAlex.
- A Systematic Review of Community Pharmacy-Led Depression Services: Service Components, Outcomes, and Implementation Barriers and Facilitators.Depression and anxiety · 2026Pooled it
- Impact of pharmacist intervention on adherence and measurable patient outcomes among depressed patients: a randomised controlled study.BMC psychiatry · 2015Trial
- Contextual analysis of antibiotic prescribing practices for upper respiratory infections and diarrhoea in rural Punjab, Pakistan.Antimicrobial resistance and infection control · 2026Article
- Understanding Adherence to Duloxetine in Psychiatric Practice: A Cross-Sectional Evaluation of Clinicians' Experience.Brain sciences · 2026Article
- Impact of pharmaceutical care interventions on antidepressants adherence and clinical outcomes in depressed patients: A systematic review.Exploratory research in clinical and social pharmacy · 2025Review
- A qualitative exploration of community pharmacist views on providing a mental health and well-being intervention for long-term condition patients.Exploratory research in clinical and social pharmacy · 2025Article
- Patterns and Appropriateness of Psychotropic Medications Prescribing in Primary Healthcare in Jordan.Pharmacy (Basel, Switzerland) · 2025Article
- The evolving role of pharmacists in depression care: a scoping review.International journal of clinical pharmacy · 2024Article
- Between what is and what could be: a survey of pharmacists' practices, attitudes, and beliefs in the provision of mental health care.International journal of clinical pharmacy · 2023Article
- Evaluation of pharmaceutical care services in the Middle East Countries: a review of studies of 2013-2020.BMC public health · 2023Review
- The Effect of Patients' Psychological Contract with Pharmacists on Medication Adherence: A Qualitative Study.Patient preference and adherence · 2023Article
- Impact of Pharmacist Intervention on Medication Adherence and Patient-Reported Outcomes among Depressed Patients in a Private Psychiatric Hospital of Nepal: a randomised controlled trial.Hospital pharmacy · 2022Article
- A qualitative exploration of mental health services provided in community pharmacies.PloS one · 2022Article
- Pharmacists' roles in supporting people living with severe and persistent mental illness: a systematic review protocol.BMJ open · 2020Article
- The Potential Role of the Pharmacist in Supporting Patients with Depression - A Literature-Based Point of View.Integrated pharmacy research & practice · 2020Review
- Correlation Between Patients' Medication Adherence and Their Psychological Contract with Hospital Pharmacists.Patient preference and adherence · 2020Article
- Barriers interfering with establishment of Collaborative Drug Therapy Management (CDTM) agreements between clinical pharmacists and physicians.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2019Article
- Using Dispensing Data to Evaluate Adherence Implementation Rates in Community Pharmacy.Frontiers in pharmacology · 2019Article
- The Development of a Community Pharmacy-Based Intervention to Optimize Patients' Use of and Experience with Antidepressants: A Step-by-Step Demonstration of the Intervention Mapping Process.Pharmacy (Basel, Switzerland) · 2018Article
- The impact of a pharmacist-led educational interview on medication adherence of Saudi patients with epilepsy.Patient preference and adherence · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPharmacist intervention in improving patient adherence to antidepressants is coupled with better outcomes.
aimsThe aim of this investigation was to systematically examine the published literature to explore different types of pharmacist interventions used for enhancing patient adherence to antidepressant medications. Three specific questions guided the review: what is the impact of pharmacist interventions on adherence to antidepressant medication? What is the impact of pharmacist interventions on patient-reported outcomes and patient satisfactions? What are the types of interventions used by pharmacists to enhance patients' adherence to antidepressants? SEARCH STRATEGIES: A systematic review of the literature was conducted during August-November 2010 using PubMed, BIOSIS Previews(®) Web of Science, ScienceDirect, the Cochrane Library, PsycINFO(®), IngentaConnect™, Cambridge Journals Online, and Medscape databases. Key text words and medical subject headings included pharmacist intervention, medication intervention, depression, medication adherence, health-related quality of life, patient-reported outcomes, and antidepressants.
resultsA total of 119 peer-reviewed papers were retrieved; 94 were excluded on the basis of abstract review and 13 after full-text analysis, resulting in twelve studies suitable for inclusion and intensive review. The most common intervention strategy that pharmacists utilized was a combination of patient education and drug monitoring. A cumulative patient adherence improvement in this review ranged from 15% to 27% attributed to utilization of different interventions and different combinations of interventions together with patient satisfaction with the treatment when depression improved.
conclusionThis review suggests that pharmacist intervention is effective in the improvement of patient adherence to antidepressants. This may be a basis for more studies examining the effectiveness of innovative interventions by pharmacists to enhance patient adherence to antidepressant medications.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.