ArticleIndian journal of pharmacology2012
Evaluation of the effect of Ferula asafoetida Linn. gum extract on learning and memory in Wistar rats.
Article in Indian journal of pharmacology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 75 citations in OpenAlex.
- Neurocaf™, A green coffee bean extract containing eicosanoyl-5-hydroxytryptamide and chlorogenic acids enhances cognitive function and neuronal plasticity in a scopolamine-induced amnesia mouse model.Metabolic brain disease · 2026Article
- Article
- Effect of Ferula sp. on sperm cryotolerance, quality, and fatty acid composition in common carp (Cyprinus carpio).Veterinary research communications · 2025Article
- Osteo-inductive potential of homoeopathy potencies of Asafoetida on multipotent mesenchymal stem cells in vitro.3 Biotech · 2025Article
- Review
- A Comprehensive Review of the Pharmacological Effects of Genus Ferula on Central Nervous System Disorders.Central nervous system agents in medicinal chemistry · 2024Review
- Review of potential spermatogenic and aphrodisiac effects of the Ferula genus.Clinical and experimental reproductive medicine · 2023Article
- Neuroprotective potency of some spice herbs, a literature review.Journal of traditional and complementary medicine · 2019Review
- Biological activities and medicinal properties of Asafoetida: A review.Journal of traditional and complementary medicine · 2017Review
- Avicenna's pharmacological approach to memory enhancement.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2017Review
- Natural Products Screening for the Identification of Selective Monoamine Oxidase-B Inhibitors.European journal of medicinal plants · 2016Article
- Influence of asafoetida on prevention and treatment of memory impairment induced by d-galactose and NaNO2 in mice.American journal of Alzheimer's disease and other dementias · 2015Article
- Crocin improved learning and memory impairments in streptozotocin-induced diabetic rats.Iranian journal of basic medical sciences · 2013Article
- Role of the potassium channels in vasorelaxant effect of asafoetida essential oil.Avicenna journal of phytomedicineArticle
- Anxiolytic, antidepressant, and antistress activities of the aqueous extract ofIndian journal of pharmacologyArticle
- Calotropis procera: A potential cognition enhancer in scopolamine and electroconvulsive shock-induced amnesia in rats.Indian journal of pharmacologyArticle
- Evaluation of neuroprotective effect of quercetin with donepezil in scopolamine-induced amnesia in rats.Indian journal of pharmacologyArticle
- Protective Effect of Standardized Extract ofAncient science of lifeArticle
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveMemory loss is universal and is the first symptom to manifest in majority of the patients suffering from Alzheimer's disease. This study is designed to investigate the effect of Ferula asafoetida linn. (F. foetida) extract on learning and memory in rats. MATERIALS AND
methodsLearning and memory were evaluated using elevated plus maze and passive avoidance paradigm after the oral administration of two doses (200 mg/kg and 400 mg/kg) of F. foetida aqueous extract with rivastigmine as positive control. Brain cholinesterase activity, serum thiols and cholesterol were also estimated.
resultsExtract produced significant improvement in memory score i.e. step through latency at 400 mg/kg dose in passive avoidance model (P< 0.05) and dose-dependent improvement of transfer latency in elevated plus maze model (P< 0.001). Dose-dependent inhibition of brain cholinesterase (P< 0.001) and significant improvement in antioxidant levels (P< 0.05) were also noted.
conclusionsMemory enhancing potential of F. foetida can be attributed to acetylcholinesterase inhibiting and antioxidant properties. Hence, dietary usage of F. foetida is beneficial and can also be employed as an adjuvant to existing anti-dementia therapies.
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