Evidence map›Paper›PMID 22345607›Full record

ReviewGenetics2012

Chromatin and transcription in yeast.

Oliver J Rando, Fred Winston

Open access · bronzeAbstract readReview
In one paragraph

Review in Genetics, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 187 papers.

0numbers the graph read from it
0cells of the map it votes in
187citing papers in PubMed
10.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

187 citing papers in PubMed, 289 citations in OpenAlex.

  1. Article
  2. High-resolution global recombination mapping inbioRxiv : the preprint server for biology · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. What makes genes burst.Trends in cell biology · 2026
    Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Review
  17. Article
  18. HPathogens (Basel, Switzerland) · 2024
    Review
  19. Article
  20. Review

127 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Oliver J RandoDepartment of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, Massachusetts 01605, USA.
Fred Winston
Harvard University · USUniversity of Massachusetts Chan Medical School · US

Funding

GENERAL TRANSCRIPTION FACTORS IN YEASTR01GM045720 · NIGMS · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI WINSTON, FRED M. · 1991 to 2011
$5.3M
Factors Controlling Transcription and Chromatin in YeastR37GM032967 · NIGMS · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI WINSTON, FRED M. · 2004 to 2013
$4.9M
INSERTION MUTATION SUPPRESSORS IN YEASTR01GM032967 · NIGMS · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI WINSTON, FRED M. · 1985 to 2017
$3.6M
NIGMS NIH HHS R01 GM032967NIGMS NIH HHS R01 GM045720NIGMS NIH HHS R37 GM032967
6 · The paper itself

Abstract

Understanding the mechanisms by which chromatin structure controls eukaryotic transcription has been an intense area of investigation for the past 25 years. Many of the key discoveries that created the foundation for this field came from studies of Saccharomyces cerevisiae, including the discovery of the role of chromatin in transcriptional silencing, as well as the discovery of chromatin-remodeling factors and histone modification activities. Since that time, studies in yeast have continued to contribute in leading ways. This review article summarizes the large body of yeast studies in this field.

Indexed as

Transcription, GeneticChromatinChromatin Assembly and DisassemblyHistonesNucleosomesOpen Reading FramesRegulatory Sequences, Nucleic AcidSaccharomyces cerevisiaeTranscriptional ActivationTranscription FactorsChromatinHistonesNucleosomesTranscription Factors

Identifiers

PMID22345607
PMCPMC3276623
OpenAlexW2166612340

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.