ReviewArteriosclerosis, thrombosis, and vascular biology2012
Critical review of mouse models of venous thrombosis.
Review in Arteriosclerosis, thrombosis, and vascular biology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 145 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
145 citing papers in PubMed.
- Mouse models to study von Willebrand factor in thrombosis: a scoping review.Research and practice in thrombosis and haemostasis · 2026Article
- Targeting α6β1 integrin signaling with pranlukast to modulate venous endothelium function and reduce post-thrombotic vein wall injury.Journal of vascular surgery. Venous and lymphatic disorders · 2026Article
- Article
- Rethinking the selection of in vivo thrombosis models in the hybrid era.Nature cardiovascular research · 2026Article
- Visualization of new vessel formation during venous thrombus organization using genetic fate mapping.Research and practice in thrombosis and haemostasis · 2026Article
- Mouse models to study von Willebrand factor in inflammation: a scoping review.Intensive care medicine experimental · 2026Review
- In vivo targeting of open prothrombin with the monoclonal antibody POmAb results in anticoagulation without excessive bleeding.Journal of thrombosis and haemostasis : JTH · 2026Article
- Targeted Thrombolysis via CCR2-Engineered Macrophage-Mimicking Microbubbles Safely Ablates Venous, Arterial, and Microvascular Thrombosis.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Inflammatory macrophages drive smooth muscle dedifferentiation via YAP signaling in murine deep vein thrombosis.Cell communication and signaling : CCS · 2026Article
- Loss of factor XIII decreases immune cell infiltration and enhances vessel wall endothelialization after venous thrombosis.Blood advances · 2026Article
- Anti-Thrombotic Activities of Veratramine via Inhibiting Platelet Aggregation and FIIa/FXa.Biology · 2026Article
- Antithrombotic Therapy on Antithrombin Resistance in a Mouse Model.Arteriosclerosis, thrombosis, and vascular biology · 2026Article
- Next Generation Experimental Models of Venous Physiology and Pathology: Examining Human Relevance in Recapitulating Lower Extremity Flow and Valve Function in New Approach Methods (NAMs).Small (Weinheim an der Bergstrasse, Germany) · 2026Review
- Animal models of antiphospholipid syndrome.Frontiers in immunology · 2026Review
- Magnetically-Induced Suppression of Oxidative Stress Prevents Venous Thrombosis.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Characterization of Arteriovenous Thrombus Formation and Propagation in a Mouse Arteriovenous Fistula Model.Thrombosis and haemostasis · 2025Article
- Methodological framework and unified metrics for thrombus resolution analysis in the mouse inferior vena cava stenosis model.Research and practice in thrombosis and haemostasis · 2025Article
- Serotonin transporter deficiency, but not absence of platelet serotonin, impairs thrombus formation in a model of deep vein thrombosis.Research and practice in thrombosis and haemostasis · 2025Article
- Recent Pathophysiological Insights Are Advancing the Treatment of Venous Thromboembolism.JACC. Basic to translational science · 2025Review
- A mouse model of deep vein thrombosis by inferior vena cava hypoperfusion using ameroid constrictors.Scientific reports · 2025Article
85 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
Deep vein thrombosis and pulmonary embolism are a significant health care concern, representing a major source of mortality and morbidity. In order to understand the pathophysiology of thrombogenesis and thrombus resolution, animal models are necessary. Mouse models of venous thrombosis contribute to our understanding of the initiation, propagation, and resolution of venous thrombus, as well as allow for the evaluation of new pharmaceutical approaches to prophylaxis and treatment of deep vein thrombosis. In this work we review the ferric chloride model, the inferior vena cava ligation model, the inferior vena cava stenosis models, and the electrolytic inferior vena cava model and compare their advantages and disadvantages.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.