ReviewWiley interdisciplinary reviews. Systems biology and medicine
Linking genome to epigenome.
Review in Wiley interdisciplinary reviews. Systems biology and medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Association between childhood asthma and history of assisted reproduction techniques: a systematic review and meta-analysis.European journal of pediatrics · 2021Pooled it
- Predicting regional somatic mutation rates using DNA motifs.PLoS computational biology · 2023Article
- An Update in Epigenetics in Metabolic-Associated Fatty Liver Disease.Frontiers in medicine · 2021Review
- Deep learning architectures for prediction of nucleosome positioning from sequences data.BMC bioinformatics · 2018Article
- The Ever-Evolving Concept of the Gene: The Use of RNA/Protein Experimental Techniques to Understand Genome Functions.Frontiers in molecular biosciences · 2018Review
- Inferring Past Environments from Ancient Epigenomes.Molecular biology and evolution · 2017Article
- Epigenetics and Liver Fibrosis.Cellular and molecular gastroenterology and hepatology · 2017Review
- Differential Response to High Glucose in Skin Fibroblasts of Monozygotic Twins Discordant for Type 1 Diabetes.The Journal of clinical endocrinology and metabolism · 2015Article
- Predicting the human epigenome from DNA motifs.Nature methods · 2015Article
- Applications of alignment-free methods in epigenomics.Briefings in bioinformatics · 2014Review
- Analysis of chromatin-state plasticity identifies cell-type-specific regulators of H3K27me3 patterns.Proceedings of the National Academy of Sciences of the United States of America · 2014Article
- A symbiotic liaison between the genetic and epigenetic code.Frontiers in genetics · 2014Review
- Current issues in medically assisted reproduction and genetics in Europe: research, clinical practice, ethics, legal issues and policy. European Society of Human Genetics and European Society of Human Reproduction and Embryology.European journal of human genetics : EJHG · 2013Article
- Modeling the dynamics of bivalent histone modifications.PloS one · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
Abstract
Recent epigenomic studies have identified significant differences between developmental stages and cell types. While the importance of epigenetic regulation has been increasingly recognized, it remains unclear how the global epigenetic patterns are established and maintained. Here I review a number of recent studies with the emphasis on the role of the genomic sequence in shaping the epigenetic landscape. These studies strongly suggest that the sequence information is important not just for controlling target specificity but for orchestrating the diversity of epigenetic patterns among different cell types. The epigenome is maintained by the complex network of a large number of interactions. Integrative approaches are needed to gain insights into these networks.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.