ReviewGenesis (New York, N.Y. : 2000)2012
The hitchhiker's guide to Xenopus genetics.
Review in Genesis (New York, N.Y. : 2000), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 29 citations in OpenAlex.
- Retention and tissue-specific expression of uncoupling protein homoeologs in Xenopus laevis.Biology open · 2026Article
- Inbred strains of Xenopus tropicalis show morphological and genetic variation.Scientific reports · 2026Article
- CRISPR/Cas9 Gene Disruption Studies in FMethods in molecular biology (Clifton, N.J.) · 2023Article
- The Zahn drawings: new illustrations ofDevelopment (Cambridge, England) · 2017Article
- Subfunctionalization of Paralogous Aryl Hydrocarbon Receptors from the Frog Xenopus Laevis: Distinct Target Genes and Differential Responses to Specific Agonists in a Single Cell Type.Toxicological sciences : an official journal of the Society of Toxicology · 2017Article
- Xenopus borealis as an alternative source of oocytes for biophysical and pharmacological studies of neuronal ion channels.Scientific reports · 2015Article
- Cas9-based genome editing in Xenopus tropicalis.Methods in enzymology · 2014Article
- Simple and efficient CRISPR/Cas9-mediated targeted mutagenesis in Xenopus tropicalis.Genesis (New York, N.Y. : 2000) · 2013Article
- Inversion of left-right asymmetry alters performance ofAnimal behaviour · 2013Article
- Article
- Evolution and development of the tetrapod auditory system: an organ of Corti-centric perspective.Evolution & development · 2013Review
- Exon capture and bulk segregant analysis: rapid discovery of causative mutations using high-throughput sequencing.BMC genomics · 2012Article
- Understanding the evolution and development of neurosensory transcription factors of the ear to enhance therapeutic translation.Cell and tissue research · 2012Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
Abstract
A decade after the human genome sequence, most vertebrate gene functions remain poorly understood, limiting benefits to human health from rapidly advancing genomic technologies. Systematic in vivo functional analysis is ideally suited to the experimentally accessible Xenopus embryo, which combines embryological accessibility with a broad range of transgenic, biochemical, and gain-of-function assays. The diploid X. tropicalis adds loss-of-function genetics and enhanced genomics to this repertoire. In the last decade, diverse phenotypes have been recovered from genetic screens, mutations have been cloned, and reverse genetics in the form of TILLING and targeted gene editing have been established. Simple haploid genetics and gynogenesis and the very large number of embryos produced streamline screening and mapping. Improved genomic resources and the revolution in high-throughput sequencing are transforming mutation cloning and reverse genetic approaches. The combination of loss-of-function mutant backgrounds with the diverse array of conventional Xenopus assays offers a uniquely flexible platform for analysis of gene function in vertebrate development.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.