Evidence map›Paper›PMID 22344361›Full record

ReviewSao Paulo medical journal = Revista paulista de medicina2012

Paraganglioma of seminal vesicle and chromophobe renal cell carcinoma: a case report and literature review.

César Augusto Alvarenga, José Manuel Lopes, João Vinagre, Paula Itagyba Paravidino, Marcelo Alvarenga, Adilson Prando, Lísias Nogueira Castilho, Paula Soares, Athanase Billis

Open access · diamondAbstract readCase ReportsReview
In one paragraph

Review in Sao Paulo medical journal = Revista paulista de medicina, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 15 citations in OpenAlex.

  1. Primary Paraganglioma of Seminal Vesicle.Chinese medical journal · 2016
    Article
  2. Article
  3. Article
  4. Article
  5. Primary paraganglioma of seminal vesicle.International journal of surgery case reports · 2013
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 2 countries.

César Augusto AlvarengaDepartment of Pathology, Universidade Estadual de Campinas, Campinas, São Paulo, Brazil. cesalvarenga@gmail.com
José Manuel Lopes
João Vinagre
Paula Itagyba Paravidino
Marcelo Alvarenga
Adilson Prando
Lísias Nogueira Castilho
Paula Soares
Athanase Billis
Universidade Estadual de Campinas (UNICAMP) · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

contextExtra-adrenal paragangliomas are rare tumors that have been reported in many locations, including the kidney, urethra, urinary bladder, prostate, spermatic cord, gallbladder, uterus and vagina. CASE REPORT: This report describes, for the first time to the best of our knowledge, a primary paraganglioma of the seminal vesicle occurring in a 61-year-old male. The patient presented persistent arterial hypertension and a previous diagnosis of chromophobe renal cell carcinoma. It was hypothesized that the seminal vesicle tumor could be a metastasis from the chromophobe renal cell carcinoma. Immunohistochemical characterization revealed expression of synaptophysin and chromogranin in tumor cell nests and peripheral S100 protein expression in sustentacular cells. Succinate dehydrogenase A and B-related (SDHA and SDHB) expression was present in both tumors.

conclusionsNo genetic alterations to the VHL and SDHB genes were detected in either the tumor tissue or tissues adjacent to the tumor, which led us to rule out a hereditary syndrome that could explain the association between paraganglioma and chromophobe renal cell carcinoma in a patient with arterial hypertension.

Indexed as

Carcinoma, Renal CellDiagnosis, DifferentialGenital Neoplasms, MaleHumansHypertensionKidney NeoplasmsMaleMiddle AgedNeoplasms, Multiple PrimaryParagangliomaSeminal VesiclesSuccinate DehydrogenaseVon Hippel-Lindau Tumor Suppressor ProteinSDHB protein, humanSuccinate DehydrogenaseVHL protein, humanVon Hippel-Lindau Tumor Suppressor Protein

Identifiers

PMID22344361
PMCPMC10906681
OpenAlexW2086462927

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.