Evidence map›Paper›PMID 22342531›Full record

ReviewBiochimica et biophysica acta2012

Retrotransposons at Drosophila telomeres: host domestication of a selfish element for the maintenance of genome integrity.

Liang Zhang, Yikang S Rong

Abstract readReview
In one paragraph

Review in Biochimica et biophysica acta, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Science advances · 2023
    Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. The role of transposable elements in health and diseases of the central nervous system.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2013
    Review
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Liang ZhangLaboatory of Biochechemistry and Molecular Biology, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.
Yikang S Rong

Funding

DNA Double Strand Break Repair in Drosophila MelanogasterZIABC010446 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI RONG, YIKANG · 2009 to 2015
$6.9M
Intramural NIH HHS ZIA BC010446
6 · The paper itself

Abstract

Telomere serves two essential functions for the cell. It prevents the recognition of natural chromosome ends as DNA breaks (the end capping function). It counteracts incomplete end replication by adding DNA to the ends of chromosomes (the end elongation function). In most organisms studied, telomerase fulfills the end elongation function. In Drosophila, however, telomere specific retrotransposons have been coerced into performing this essential function for the host. In this review, we focus our discussion on transposition mechanisms and transcriptional regulation of these transposable elements, and present provocative models for the purpose of spurring new interests in the field. This article is part of a Special Issue entitled: Chromatin in time and space.

Indexed as

RetroelementsAnimalsChromosomes, InsectDrosophilaGene Expression Regulation, DevelopmentalGenomic InstabilityHumansMutagenesis, InsertionalRepetitive Sequences, Nucleic AcidRNA, MessengerTelomereRetroelementsRNA, Messenger

Identifiers

PMID22342531
PMCPMC3360995

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.