Evidence map›Paper›PMID 22342514›Full record

ReviewInfection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases2012

Molecular methods for pathogen and microbial community detection and characterization: current and potential application in diagnostic microbiology.

Christopher D Sibley, Gisele Peirano, Deirdre L Church

Abstract readReview
In one paragraph

Review in Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

55 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. The use of genetic markers in the molecular epidemiology of histoplasmosis: a systematic review.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2016
    Pooled it
  2. Review
  3. Review
  4. Observational
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. High Prevalence of a Novel Circovirus in the European Hedgehog (Transboundary and emerging diseases · 2024
    Article
  12. Biophysical reviews · 2023
    Review
  13. Antimicrobial resistance in bacteria isolated from peridomesticOne health (Amsterdam, Netherlands) · 2023
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Microorganisms · 2020
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Christopher D SibleyDepartment of Microbiology, Immunology & Infectious Diseases, University of Calgary, Calgary, Alta, Canada.
Gisele Peirano
Deirdre L Church

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Clinical microbiology laboratories worldwide have historically relied on phenotypic methods (i.e., culture and biochemical tests) for detection, identification and characterization of virulence traits (e.g., antibiotic resistance genes, toxins) of human pathogens. However, limitations to implementation of molecular methods for human infectious diseases testing are being rapidly overcome allowing for the clinical evaluation and implementation of diverse technologies with expanding diagnostic capabilities. The advantages and limitation of molecular techniques including real-time polymerase chain reaction, partial or whole genome sequencing, molecular typing, microarrays, broad-range PCR and multiplexing will be discussed. Finally, terminal restriction fragment length polymorphism (T-RFLP) and deep sequencing are introduced as technologies at the clinical interface with the potential to dramatically enhance our ability to diagnose infectious diseases and better define the epidemiology and microbial ecology of a wide range of complex infections.

Indexed as

Genome, BacterialGenome, FungalBacteriaCommunicable DiseasesComputational BiologyFungiGenotyping TechniquesHumansMicroarray AnalysisMicrobiological TechniquesMolecular TypingPolymerase Chain ReactionPolymorphism, Restriction Fragment LengthReagent Kits, DiagnosticReagent Kits, Diagnostic

Identifiers

PMID22342514
PMCPMC7106020

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.