GuidelineFertility and sterility2012
Executive summary of the Stages of Reproductive Aging Workshop + 10: addressing the unfinished agenda of staging reproductive aging.
Guideline in Fertility and sterility, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 66 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effects of a Tissue Selective Estrogen Complex (TESC) on Depression and the Neural Reward System in the Perimenopause
Examining the Effects of Estradiol on Neural and Molecular Response to Rewards in Perimenopausal-Onset Anhedonia and Psychosis
Who cites it
66 citing papers in PubMed, 3 syntheses or guidelines pooled it, 235 citations in OpenAlex.
- Pooled it
- Lifestyle interventions targeting body weight changes during the menopause transition: a systematic review.Journal of obesity · 2014Pooled it
- Phytoestrogens for menopausal vasomotor symptoms.The Cochrane database of systematic reviews · 2013Pooled it
- The efficacy and safety of Femoston combined with Baoqing granules for kidney Yin deficiency in perimenopausal women: a randomized, double-blind, placebo-controlled trial.Frontiers in endocrinology · 2026Trial
- Clinical Research of the Application of Bone Turnover Markers in Monitoring the Short-Term Therapeutic Efficacy of Vitamin D in Postmenopausal Osteoporotic women in Harbin, China.The journal of nutrition, health & aging · 2020Trial
- Acupuncture for menopausal vasomotor symptoms: study protocol for a randomised controlled trial.Trials · 2014Trial
- Psychometric properties of the Chinese version of the Meno-D in perimenopausal women.BMC women's health · 2026Article
- Machine learning prediction for menopause women with low bone mass: a multicenter and retrospective study.Scientific reports · 2026Article
- Impact of Menopausal Status and Female Reproductive Aging on the Outcomes of Bariatric Surgery: A Narrative Review.Cureus · 2026Review
- Adiposity and reproductive characteristics across the lifespan: a multi-ethnic population-based study in Northwest China.Reproductive health · 2026Article
- Menopause is not associated with asthma or severe asthma.The journal of allergy and clinical immunology. In practice · 2025Article
- Reconsidering Hormone Replacement Therapy: Current Insights on Utilisation in Premenopausal and Menopausal Women: An Overview.Journal of clinical medicine · 2025Review
- The Final Phases of Ovarian Aging: A Tale of Diverging Functional Trajectories.Journal of clinical medicine · 2025Review
- Associations between lifetime reproductive events among postmenopausal women with bipolar disorder.Archives of women's mental health · 2025Article
- Follicle-stimulating hormone: More than a marker for menopause: FSH as a frontier for women's mental health.Psychiatry research · 2025Review
- Menopausal hormone therapy and exercise on psychosocial well-being and stress in menopausal women.Frontiers in reproductive health · 2025Article
- A research protocol using ECG monitoring for detection of palpitations-associated arrhythmias in breast cancer survivors.PloS one · 2025Article
- Integrated analysis of metabolome and microbiome in a rat model of perimenopausal syndrome.mSystems · 2024Article
- The menopausal transition period and cardiovascular risk.Nature reviews. Cardiology · 2024Review
- Stress, depression, and anxiety: psychological complaints across menopausal stages.Frontiers in psychiatry · 2024Article
6 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 8 institutions in 1 country.
Funding
Abstract
objectiveThe aim of this article is to summarize the recommended updates to the 2001 Stages of Reproductive Aging Workshop (STRAW) criteria. The 2011 STRAW + 10 reviewed advances in understanding of the critical changes in hypothalamic-pituitary-ovarian function that occur before and after the final menstrual period. METHOD(S): Scientists from five countries and multiple disciplines evaluated data from cohort studies of midlife women and in the context of chronic illness and endocrine disorders on change in menstrual, endocrine, and ovarian markers of reproductive aging including antimüllerian hormone, inhibin-B, follicle-stimulating hormone, and antral follicle count. Modifications were adopted by consensus. RESULT(S): STRAW + 10 simplified bleeding criteria for the early and late menopausal transition, recommended modifications to criteria for the late reproductive stage (Stage -3) and the early postmenopause stage (Stage +1), provided information on the duration of the late transition (Stage -1) and early postmenopause (Stage +1), and recommended application regardless of women's age, ethnicity, body size, or lifestyle characteristics. CONCLUSION(S): STRAW + 10 provides a more comprehensive basis for assessing reproductive aging in research and clinical contexts. Application of the STRAW + 10 staging system should improve comparability of studies of midlife women and facilitate clinical decision making. Nonetheless, important knowledge gaps persist, and seven research priorities are identified.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.