Evidence map›Paper›PMID 22341538›Full record

ReviewClinics in perinatology2012

The use of antiviral drugs during the neonatal period.

Richard J Whitley

Abstract readReview
In one paragraph

Review in Clinics in perinatology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 42 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Bilateral cytomegalovirus retinitis in a healthy infant.Journal of current ophthalmology · 2017
    Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Neonatal Herpes Simplex Viral Infections and Acyclovir: An Update.The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Richard J WhitleyDepartment of Pediatrics, The University of Alabama at Birmingham, 1600 7th Avenue South, Birmingham, AL 35233-1711, USA. RWhitley@peds.uab.edu
University of Alabama at Birmingham · US

Funding

UAB Skin Diseases Research CenterP30AR050948 · NIAMS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI BELLIS, SUSAN L · 2004 to 2013
$5.5M
CLINICAL TRIALS FOR ANTIVIRAL THERAPIES-266030025-266030025N01AI030025 · NIAID · UNIVERSITY OF ALABAMA BIRMINGH · PI WHITLEY, RICHARD R · 2003 to 2006
–
NIAID NIH HHS N01 AI030025NIAMS NIH HHS P30 AR050948
6 · The paper itself

Abstract

Parenteral therapy of viral infections of the newborn and infant began with vidarabine (adenine arabinoside) for the treatment of neonatal herpes simplex virus (HSV) infections in the early 1980s. Acyclovir has become the treatment of choice for neonatal HSV infections and a variety of other herpesvirus infections. Ganciclovir is beneficial for the treatment of congenital cytomegalovirus (CMV) infections involving the central nervous system (CNS). This article reviews the use of acyclovir and ganciclovir in the treatment of neonatal HSV and congenital CMV infections. A brief summary precedes a detailed discussion of available established and alternative therapeutics.

Indexed as

AcyclovirAntiviral AgentsChickenpoxCytomegalovirus InfectionsDrug InteractionsFemaleGanciclovirHerpes SimplexHumansInfant, NewbornInfant, Newborn, DiseasesPregnancyAcyclovirAntiviral AgentsGanciclovir

Identifiers

PMID22341538
PMCPMC3290126
OpenAlexW2004965405

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.