Evidence map›Paper›PMID 22340831›Full record

ReviewJACC. Cardiovascular imaging2012

Targeted metabolic imaging to improve the management of heart disease.

Moritz Osterholt, Shiraj Sen, Vasken Dilsizian, Heinrich Taegtmeyer

Abstract readReview
In one paragraph

Review in JACC. Cardiovascular imaging, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Article
  6. Searching for novel PET radiotracers: imaging cardiac perfusion, metabolism and inflammation.American journal of nuclear medicine and molecular imaging · 2018
    Review
  7. Review
  8. Cardiac molecular imaging to track left ventricular remodeling in heart failure.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2017
    Review
  9. The Potential of Metabolic Imaging.Seminars in nuclear medicine · 2016
    Review
  10. Article
  11. Review
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Moritz OsterholtDepartment of Internal Medicine/Division of Cardiology, University of Texas Medical School at Houston, Houston, Texas 77030, USA.
Shiraj Sen
Vasken Dilsizian
Heinrich Taegtmeyer

Funding

SWITCHING OF METABOLIC GENES IN UNLOADED HEARTR01HL061483 · NHLBI · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI TAEGTMEYER, HEINRICH · 1999 to 2021
$6.2M
Glucolipotoxicity and Cardiac Dysfunction in ObesityR01HL073162 · NHLBI · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI TAEGTMEYER, HEINRICH · 2003 to 2007
$2.5M
PATHOPHYSIOLOGY OF CORONARY ARTERY DISEASET32HL007591 · NHLBI · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI TAEGTMEYER, HEINRICH · 1985 to 2003
$291k
NHLBI NIH HHS R01 HL061483NHLBI NIH HHS R01 HL073162NHLBI NIH HHS T32 HL007591
6 · The paper itself

Abstract

Tracer techniques are powerful methods for assessing rates of biological processes in vivo. A case in point is intermediary metabolism of energy providing substrates, a central feature of every living cell. In the heart, the tight coupling between metabolism and contractile function offers an opportunity for the simultaneous assessment of cardiac performance at different levels in vivo: coronary flow, myocardial perfusion, oxygen delivery, metabolism, and contraction. Noninvasive imaging techniques used to identify the metabolic footprints of either normal or perturbed cardiac function are discussed.

Indexed as

Magnetic Resonance SpectroscopyPositron-Emission TomographyRadiopharmaceuticalsTomography, Emission-Computed, Single-PhotonAmino AcidsEnergy MetabolismFatty AcidsGlucoseHeart DiseasesHumansMyocardiumAmino AcidsFatty AcidsGlucoseRadiopharmaceuticals

Identifiers

PMID22340831
PMCPMC3302688

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.