ReviewTranslational research : the journal of laboratory and clinical medicine2012
Molecular imaging of disease with targeted contrast ultrasound imaging.
Review in Translational research : the journal of laboratory and clinical medicine, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed.
- Contrast-enhanced ultrasound in critical care: a problem-solving approach.Frontiers in medicine · 2026Review
- Contrast-enhanced ultrasound molecular imaging of activated platelets in the progression of atherosclerosis using microbubbles bearing the von Willebrand factor A1 domain.Experimental and therapeutic medicine · 2021Article
- Endothelial vascular cell adhesion molecule 1 is a marker for high-risk carotid plaques and target for ultrasound molecular imaging.Journal of vascular surgery · 2018Article
- Advances in ultrasound-targeted microbubble-mediated gene therapy for liver fibrosis.Acta pharmaceutica Sinica. B · 2017Review
- Functional adaptations of the coronary microcirculation to anaemia in fetal sheep.The Journal of physiology · 2016Article
- Molecular Imaging of Vulnerable Atherosclerotic Plaques in Animal Models.International journal of molecular sciences · 2016Review
- Molecular Acoustic Angiography: A New Technique for High-resolution Superharmonic Ultrasound Molecular Imaging.Ultrasound in medicine & biology · 2016Article
- Ultrasound molecular imaging: Moving toward clinical translation.European journal of radiology · 2015Review
- Cardiovascular molecular imaging with contrast ultrasound: principles and applications.Korean circulation journal · 2014Review
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2 authors.
Funding
Abstract
To enhance clinical care for patients, methods for noninvasive imaging of specific disease-related molecular changes are being developed to expand and improve diagnostic capabilities. These new techniques are used in research programs to characterize pathophysiology and as a surrogate end point for therapeutic efficacy. Molecular imaging with contrast-enhanced ultrasound relies on the detection of microbubbles or other acoustically active particulate agents that are targeted to and retained at sites of disease. This review describes the progress that has been made in the development and testing of methods for contrast ultrasound molecular imaging with a specific focus on cardiovascular disease. Specific topics addressed include probe development, detection methods, and specific biologic processes that are important in clinical cardiovascular medicine and that have been targeted with microbubble contrast agents.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.