Evidence map›Paper›PMID 22339460›Full record

ReviewImmunotherapy2012

Passive immune neutralization strategies for prevention and control of influenza A infections.

Jianqiang Ye, Hongxia Shao, Daniel R Perez

Abstract readReview
In one paragraph

Review in Immunotherapy, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Passive broad-spectrum influenza immunoprophylaxis.Influenza research and treatment · 2014
    Review
  7. Article
  8. Review
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Jianqiang YeDepartment of Veterinary Medicine, University of Maryland, College Park & Virginia - Maryland Regional College of Veterinary Medicine, College Park, MD 20742, USA.
Hongxia Shao
Daniel R Perez
Yangzhou University · CN

Funding

Transmissibility of Influenza A VirusesR01AI052155 · NIAID · UNIV OF MARYLAND, COLLEGE PARK · PI PEREZ, DANIEL R · 2003 to 2006
$1.1M
Mechanisms of Influenza a Virus Transmission in FerrettsU01CI000355 · CI · UNIV OF MARYLAND, COLLEGE PARK · PI PEREZ, DANIEL R · 2006 to 2008
$400k
NCPDCID CDC HHS 1U01CI000355NCPDCID CDC HHS U01 CI000355NIAID NIH HHS HHSN266200700010CNIAID NIH HHS R01 AI052155NIAID NIH HHS R01AI052155
6 · The paper itself

Abstract

Although vaccination significantly reduces influenza severity, seasonal human influenza epidemics still cause more than 250,000 deaths annually. Vaccine efficacy is limited in high-risk populations such as infants, the elderly and immunosuppressed individuals. In the event of an influenza pandemic (such as the 2009 H1N1 pandemic), a significant delay in vaccine availability represents a significant public health concern, particularly in high-risk groups. The increasing emergence of strains resistant to the two major anti-influenza drugs, adamantanes and neuraminidase inhibitors, and the continuous circulation of avian influenza viruses with pandemic potential in poultry, strongly calls for alternative prophylactic and treatment options. In this review, we focus on passive virus neutralization strategies for the prevention and control of influenza type A viruses.

Indexed as

AnimalsHumansImmunization, PassiveInfluenza A virusInfluenza, HumanInfluenza in BirdsInfluenza VaccinesPandemicsPoultrySeasonsInfluenza Vaccines

Identifiers

PMID22339460
PMCPMC3292042
OpenAlexW2048831757

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.