Evidence map›Paper›PMID 22337986›Full record

ArticleJournal of clinical microbiology2012

Corynebacterium prosthetic joint infection.

Charles Cazanave, Kerryl E Greenwood-Quaintance, Arlen D Hanssen, Robin Patel

Open access · greenAbstract readCase ReportsValidation Study
In one paragraph

Article in Journal of clinical microbiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed, 1 pooled it
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 1 synthesis or guideline pooled it, 80 citations in OpenAlex.

  1. Pooled it
  2. Deep Spinal Infection Caused byInfection and drug resistance · 2026
    Article
  3. Article
  4. Antibiotic resistance profiles of seven genomospecies ofJournal of clinical microbiology · 2025
    Article
  5. Good Results for PJI Caused byOpen forum infectious diseases · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Microorganisms · 2023
    Article
  10. Review
  11. Article
  12. Article
  13. Clinical Profile of MonomicrobialOpen forum infectious diseases · 2022
    Article
  14. Distribution ofVeterinary sciences · 2022
    Article
  15. Diagnosing Fracture-Related Infections: Where Are We Now?Journal of clinical microbiology · 2022
    Article
  16. Review
  17. Article
  18. Article
  19. Clinical characteristics ofNagoya journal of medical science · 2021
    Observational
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Charles CazanaveDivision of Clinical Microbiology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA.
Kerryl E Greenwood-Quaintance
Arlen D Hanssen
Robin Patel
Mayo Clinic · USMayo Clinic in Florida · USUniversity of Rochester · US

Funding

Molecular Detection of Biofilms on Hip and Knee ImplantsR01AR056647 · NIAMS · MAYO CLINIC ROCHESTER · PI PATEL, ROBIN · 2009 to 2020
$4.5M
NIAMS NIH HHS R01 AR056647
6 · The paper itself

Abstract

Identification of Corynebacterium species may be challenging. Corynebacterium species are occasional causes of prosthetic joint infection (PJI), but few data are available on the subject. Based on the literature, C. amycolatum, C. aurimucosum, C. jeikeium, and C. striatum are the most common Corynebacterium species that cause PJI. We designed a rapid PCR assay to detect the most common human Corynebacterium species, with a specific focus on PJI. A polyphosphate kinase gene identified using whole-genome sequence was targeted. The assay differentiates the antibiotic-resistant species C. jeikeium and C. urealyticum from other species in a single assay. The assay was applied to a collection of human Corynebacterium isolates from multiple clinical sources, and clinically relevant species were detected. The assay was then tested on Corynebacterium isolates specifically associated with PJI; all were detected. We also describe the first case of C. simulans PJI.

Indexed as

Bacterial ProteinsBacteriological TechniquesCorynebacteriumCorynebacterium InfectionsHumansJointsMolecular Diagnostic TechniquesPhosphotransferases (Phosphate Group Acceptor)Polymerase Chain ReactionProsthesis-Related InfectionsBacterial ProteinsPhosphotransferases (Phosphate Group Acceptor)polyphosphate kinase

Identifiers

PMID22337986
PMCPMC3347109
OpenAlexW2109710105

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.