ArticleJournal of clinical microbiology2012
Molecular characterization of human enteroviruses in the Central African Republic: uncovering wide diversity and identification of a new human enterovirus A71 genogroup.
Article in Journal of clinical microbiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers, 1 of them a synthesis that pooled it.
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Who cites it
55 citing papers in PubMed, 1 synthesis or guideline pooled it, 96 citations in OpenAlex.
- Geographical distribution of enteric pathogenic viruses in Burkina Faso: a systematic review and meta-analysis.BMC infectious diseases · 2024Pooled it
- Respiratory Pathogen Detection Among Febrile Inpatients in Northern Tanzania, 2016-2019.Open forum infectious diseases · 2026Article
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- The use of sialic acids as attachment factors is a common feature ofJournal of virology · 2025Article
- Direct amplification and sequencing of enterovirus genomes from clinical and wastewater samples reveals uncommon virus types in Cameroon.Archives of virology · 2025Article
- Molecular characterization of enteroviruses circulating among pigs and goats in two Central African countries, Cameroon and the Central African Republic.Access microbiology · 2025Article
- The genetic and proliferation characterization analysis of novel coxsackievirus A12 in Beijing, China.Frontiers in microbiology · 2025Article
- Characterization of enteroviruses circulating among farm animals and children in Central African Republic.Emerging microbes & infections · 2024Article
- High Detection Frequency of Vaccine-Associated Polioviruses and Non-Polio Enteroviruses in the Stools of Asymptomatic Infants from the Free State Province, South Africa.Microorganisms · 2024Article
- Estimating prevalence of Enterovirus D111 in human and non-human primate populations using cross-sectional serology.The Journal of general virology · 2023Article
- Enterovirus detection in different regions of Madagascar reveals a higher abundance of enteroviruses of species C in areas where several outbreaks of vaccine-derived polioviruses occurred.BMC infectious diseases · 2022Article
- National Surveillance of Acute Flaccid Paralysis Cases in Senegal during 2017 Uncovers the Circulation of Enterovirus Species A, B and C.Microorganisms · 2022Article
- Molecular Epidemiology of Enterovirus A71 in Surveillance of Acute Flaccid Paralysis Cases in Senegal, 2013-2020.Vaccines · 2022Article
- Environmental Monitoring for Enteroviruses in Maputo, Mozambique-2018.Pathogens (Basel, Switzerland) · 2022Article
- A single mutation in theEmerging microbes & infections · 2021Article
- Genetic diversity and evolution of enterovirus A71 subgenogroup C1 from children with hand, foot, and mouth disease in Thailand.Archives of virology · 2021Article
- Molecular characterization of non-polio enteroviruses isolated from acute flaccid paralysis patients in Uganda.Journal of medical virology · 2021Article
- Further considerations about "Detection and identification of enteroviruses circulating in children with acute gastroenteritis in Pará State, Northern Brazil (2010-2011)".Virology journal · 2021Article
- Molecular Characterization of Coxsackievirus A24v from Feces and Conjunctiva Reveals Epidemiological Links.Microorganisms · 2021Article
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Human enteroviruses (HEV) are among the most common viruses infecting humans. Their circulation has been widely studied in most parts of the world but not in sub-Saharan Africa, where poliomyelitis remains prevalent. We report here the molecular characterization of 98 nonpoliovirus (non-PV) HEV strains isolated from 93 randomly selected cell culture-positive supernatants from stool samples collected from 1997 through 2006 from children with acute flaccid paralysis living in the Central African Republic (CAR). The isolates were typed by sequencing the VP1 coding region and sequenced further in the VP2 coding region, and phylogenetic studies were carried out. Among the 98 VP1 sequences, 3, 74, 18, and 3 were found to belong to the HEV-A, -B, -C, and -D species, respectively. Overall, 42 types were detected. In most cases, the VP2 type was correlated with that of the VP1 region. Some of the isolates belonged to lineages that also contain viruses isolated in distant countries, while others belonged to lineages containing viruses isolated only in Africa. In particular, one isolate (type EV-A71) did not fall into any of the genogroups already described, indicating the existence of a previously unknown genogroup for this type. These results illustrate the considerable diversity of HEV isolates from the stools of paralyzed children in the CAR. The presence of diverse HEV-C types makes recombination between poliovirus and other HEV-C species possible and could promote the emergence of recombinant vaccine-derived polioviruses similar to those that have been implicated in repeated poliomyelitis outbreaks in several developing countries.
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