ArticleMolecular biology of the cell2012
Some lessons about models from Michaelis and Menten.
Article in Molecular biology of the cell, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 22 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed.
- Data-driven identification of biological systems using multi-scale analysis.PLoS computational biology · 2025Article
- Thermodynamic bounds on ultrasensitivity in covalent switching.Biophysical journal · 2023Article
- The linear framework: using graph theory to reveal the algebra and thermodynamics of biomolecular systems.Interface focus · 2022Review
- A forecast for large-scale, predictive biology: Lessons from meteorology.Cell systems · 2021Review
- Robustness and parameter geography in post-translational modification systems.PLoS computational biology · 2020Article
- From Gregor Mendel to Eric Davidson: Mathematical Models and Basic Principles in Biology.Journal of computational biology : a journal of computational molecular cell biology · 2019Article
- Modeling cell population dynamics.In silico biology · 2019Article
- Integrative biological simulation praxis: Considerations from physics, philosophy, and data/model curation practices.Cellular logistics · 2017Article
- The (Mathematical) Modeling Process in Biosciences.Frontiers in genetics · 2015Review
- Beware the tail that wags the dog: informal and formal models in biology.Molecular biology of the cell · 2014Article
- Stochastic simulation in systems biology.Computational and structural biotechnology journal · 2014Review
- Models in biology: 'accurate descriptions of our pathetic thinking'.BMC biology · 2014Article
- Role of substrate unbinding in Michaelis-Menten enzymatic reactions.Proceedings of the National Academy of Sciences of the United States of America · 2014Article
- Time-scale separation--Michaelis and Menten's old idea, still bearing fruit.The FEBS journal · 2014Review
- ERK as a model for systems biology of enzyme kinetics in cells.Current biology : CB · 2013Review
- Biology is more theoretical than physics.Molecular biology of the cell · 2013Article
- Logic modeling and the ridiculome under the rug.BMC biology · 2012Article
- Realistic enzymology for post-translational modification: zero-order ultrasensitivity revisited.Journal of theoretical biology · 2012Article
- Silicon dreams of cells into symbols.Nature biotechnology · 2012Article
- Article
Corrections and comments
- Erratum issued
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Michaelis and Menten's classic 1913 paper on enzyme kinetics is used to draw some lessons about the relationship between mathematical models and biological reality.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.