ArticleWorld journal for pediatric & congenital heart surgery2011
Sepsis in the pediatric cardiac intensive care unit.
Article in World journal for pediatric & congenital heart surgery, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.
- Risk factors for acute kidney injury after pediatric cardiac surgery: a meta-analysis.Pediatric nephrology (Berlin, Germany) · 2022Pooled it
- Clinical presentations and diagnostic approaches of pediatric necrotizing tracheobronchitis with influenza A virus and Staphylococcus aureus co-infections.Scientific reports · 2024Article
- Clinical usefulness of NT-proBNP as a prognostic factor for septic shock patients presenting to the emergency department.Scientific reports · 2024Article
- Biomarker-based risk model to predict persistent multiple organ dysfunctions after congenital heart surgery: a prospective observational cohort study.Critical care (London, England) · 2023Observational
- Biomarker-based risk model to predict persistent multiple organ dysfunctions after congenital heart surgery â€" A prospective observational cohort study.Research square · 2023Article
- Correlations of Changes in Brain Natriuretic Peptide (BNP) and Cardiac Troponin I (cTnI) with Levels of C-Reactive Protein (CRP) and TNF-α in Pediatric Patients with Sepsis.Medical science monitor : international medical journal of experimental and clinical research · 2019Article
- Sepsis in Pediatric Cardiac Intensive Care.Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies · 2016Review
- Development and Validation of a Disease Severity Scoring Model for Pediatric Sepsis.Iranian journal of public health · 2016Article
- Beyond the guidelines of paediatric septic shock: A focused review.Sudanese journal of paediatrics · 2015Review
- Clinical characteristics associated with postoperative intestinal epithelial barrier dysfunction in children with congenital heart disease.Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies · 2015Article
- Pediatric sepsis: preparing for the future against a global scourge.Current infectious disease reports · 2012Article
- Risk Factors for Delayed Extubation after Ventricular Septal Defect Closure: a Prospective Observational Study.Brazilian journal of cardiovascular surgeryObservational
- Procalcitonin as a biomarker of bacterial infection in pediatric patients after congenital heart surgery.Annals of pediatric cardiologyArticle
Corrections and comments
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Authors and funding
5 authors at 4 institutions in 1 country.
Funding
Abstract
The survival rate for children with congenital heart disease (CHD) has increased significantly coincident with improved techniques in cardiothoracic surgery, cardiopulmonary bypass and myocardial protection, and perioperative care. Cardiopulmonary bypass, likely in combination with ischemia-reperfusion injury, hypothermia, and surgical trauma, elicits a complex, systemic inflammatory response that is characterized by activation of the complement cascade, release of endotoxin, activation of leukocytes and the vascular endothelium, and release of proinflammatory cytokines. This complex inflammatory state causes a transient immunosuppressed state, which may increase the risk of hospital-acquired infection in these children. Postoperative sepsis occurs in nearly 3% of children undergoing cardiac surgery and has been associated with longer length of stay and mortality risks in the pediatric cardiac intensive care unit. Herein, we review the epidemiology, pathobiology, and management of sepsis in the pediatric cardiac intensive care unit.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.