Evidence map›Paper›PMID 22336826›Full record

SynthesisThe Cochrane database of systematic reviews2012

Functional analysis-based interventions for challenging behaviour in dementia.

Esme D Moniz Cook, Katie Swift, Ian James, Reem Malouf, Marjolein De Vugt, Frans Verhey

Open access · greenAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in The Cochrane database of systematic reviews, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 9 pooled it
5.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 9 syntheses or guidelines pooled it, 132 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Simulated presence therapy for dementia.The Cochrane database of systematic reviews · 2020
    Pooled it
  5. Simulated presence therapy for dementia.The Cochrane database of systematic reviews · 2017
    Pooled it
  6. Pooled it
  7. Behavioural and psychological symptoms in dementia and the challenges for family carers: systematic review.The British journal of psychiatry : the journal of mental science · 2016
    Pooled it
  8. Pooled it
  9. Pooled it
  10. Trial
  11. Trial
  12. Agitation in dementia: Evidence-based consensus recommendations.Journal of the Chinese Medical Association : JCMA · 2026
    Review
  13. Article
  14. Caregiver perspectives enable accurate diagnosis of neurodegenerative disease.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Article
  15. Review
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 2 countries.

Esme D Moniz CookClinical Psychology & Ageing, Institute of Rehabilitation,University of Hull, Hull,UK. E.D.Moniz-Cook@hull.ac.uk
Katie Swift
Ian James
Reem Malouf
Marjolein De Vugt
Frans Verhey
University of Hull · GBCochrane · GBMaastricht University · NLMaastricht University Medical Centre · NLNorth Tyneside General Hospital · GB

Funding

Department of Health RP-PG-0606-1067
6 · The paper itself

Abstract

backgroundFunctional analysis (FA) for the management of challenging behaviour is a promising behavioural intervention that involves exploring the meaning or purpose of an individual's behaviour. It extends the 'ABC' approach of behavioural analysis, to overcome the restriction of having to derive a single explanatory hypothesis for the person's behaviour. It is seen as a first line alternative to traditional pharmacological management for agitation and aggression. FA typically requires the therapist to develop and evaluate hypotheses-driven strategies that aid family and staff caregivers to reduce or resolve a person's distress and its associated behavioural manifestations.

objectivesTo assess the effects of functional analysis-based interventions for people with dementia (and their caregivers) living in their own home or in other settings. SEARCH

methodsWe searched ALOIS: the Cochrane Dementia and Cognitive Improvement Group's Specialized Register on 3 March 2011 using the terms: FA, behaviour (intervention, management, modification), BPSD, psychosocial and Dementia. SELECTION CRITERIA: Randomised controlled trials (RCTs) with reported behavioural outcomes that could be associated with functional analysis for the management of challenging behaviour in dementia. DATA COLLECTION AND ANALYSIS: Four reviewers selected trials for inclusion. Two reviewers worked independently to extract data and assess trial quality, including bias. Meta-analyses for reported incidence, frequency, severity of care recipient challenging behaviour and mood (primary outcomes) and caregiver reaction, burden and mood were performed. Details of adverse effects were noted. MAIN

resultsEighteen trials are included in the review. The majority were in family care settings. For fourteen studies, FA was just one aspect of a broad multi-component programme of care. Assessing the effect of FA was compromised by ill-defined protocols for the duration of component parts of these programmes (i.e. frequency of the intervention or actual time spent). Therefore, establishing the real effect of the FA component was not possible.Overall, positive effects were noted at post-intervention for the frequency of reported challenging behaviour (but not for incidence or severity) and for caregiver reaction (but not burden or depression). These effects were not seen at follow-up. AUTHORS'

conclusionsThe delivery of FA has been incorporated within wide ranging multi-component programmes and study designs have varied according to setting - i.e. family care, care homes and hospital, with surprisingly few studies located in care homes. Our findings suggest potential beneficial effects of multi-component interventions, which utilise FA. Whilst functional analysis for challenging behaviour in dementia care shows promise, it is too early to draw conclusions about its efficacy.

Indexed as

Behavior TherapyCaregiversConditioning, OperantDementiaDepressionHumansMotivationRandomized Controlled Trials as TopicStress, Psychological

Identifiers

PMID22336826
PMCPMC11608818
OpenAlexW1940337650

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.