SynthesisThe Cochrane database of systematic reviews2012
Water for wound cleansing.
Synthesis in The Cochrane database of systematic reviews, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 38 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Water And Saline Head-to-head In The Blinded Evaluation Study Trial
The Irrigation or No Irrigation in Simple Lacerations Trials
Who cites it
38 citing papers in PubMed, 4 syntheses or guidelines pooled it, 237 citations in OpenAlex.
- Water for wound cleansing.The Cochrane database of systematic reviews · 2022Pooled it
- Interventions for treating bisphosphonate-related osteonecrosis of the jaw (BRONJ).The Cochrane database of systematic reviews · 2016Pooled it
- Wound management in disaster settings.World journal of surgery · 2015Pooled it
- Wound cleansing for pressure ulcers.The Cochrane database of systematic reviews · 2013Pooled it
- Postoperative socket irrigation with drinking tap water reduces the risk of inflammatory complications following surgical removal of third molars: a multicenter randomized trial.Clinical oral investigations · 2017Trial
- Article
- Review
- Ripple Effect: Safety, Cost, and Environmental Concerns of Using Sterile Water in Endoscopy.Gastro hep advances · 2025Review
- Article
- [Guidelines for neonatal skin management in the neonatal intensive care unit (2021)].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2021Article
- Transoral approach in facial penetrating trauma - importance of multidisciplinary management and nutritional support a case report.Trauma case reports · 2021Article
- The Malawi Orthopaedic Association/AO Alliance guidelines and standards for open fracture management in Malawi: a national consensus statement.Malawi medical journal : the journal of Medical Association of Malawi · 2020Article
- Simple Effective Ways to Care for Skin Wounds and Incisions.Plastic and reconstructive surgery. Global open · 2019Review
- Initial Assessment, Debridement, and Decision Making in the Salvage of Severely Injured Lower Extremity.Indian journal of plastic surgery : official publication of the Association of Plastic Surgeons of India · 2019Review
- Integrated Management of Skin NTDs-Lessons Learned from Existing Practice and Field Research.Tropical medicine and infectious disease · 2018Review
- [Primary soft tissue management in open fracture].Operative Orthopadie und Traumatologie · 2018Review
- Countermeasures against Infection in Critical Limb Ischemia Treatments.Annals of vascular diseases · 2018Article
- Open fractures of the lower extremity: Current management and clinical outcomes.EFORT open reviews · 2018Article
- Necrotizing fasciitis after scalpel injury sustained during postmortem examination.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2017Article
- Assessing and managing wounds of Buruli ulcer patients at the primary and secondary health care levels in Ghana.PLoS neglected tropical diseases · 2017Observational
Corrections and comments
- Commented on by
- Updated by
- Update of
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAlthough various solutions have been recommended for cleansing wounds, normal saline is favoured as it is an isotonic solution and does not interfere with the normal healing process. Tap water is commonly used in the community for cleansing wounds because it is easily accessible, efficient and cost effective; however, there is an unresolved debate about its use.
objectivesThe objective of this review was to assess the effects of water compared with other solutions for wound cleansing. SEARCH
methodsFor this fourth update we searched the Cochrane Wounds Group Specialised Register (searched 9 November 2011); The Cochrane Central Register of Controlled Trials (CENTRAL) (The Cochrane Library 2011, Issue 4); Ovid MEDLINE (2010 to October Week 4 2011); Ovid MEDLINE (In-Process & Other Non-Indexed Citations, November 8, 2011); Ovid EMBASE (2010 to 2011 Week 44); and EBSCO CINAHL (2010 to 4 November 2011). SELECTION CRITERIA: Randomised and quasi randomised controlled trials that compared the use of water with other solutions for wound cleansing were eligible for inclusion. Additional criteria were outcomes that included objective or subjective measures of wound infection or healing. DATA COLLECTION AND ANALYSIS: Two review authors independently carried out trial selection, data extraction and quality assessment. We settled differences in opinion by discussion. We pooled some data using a random-effects model. MAIN
resultsWe included 11 trials in this review. We identified seven trials that compared rates of infection and healing in wounds cleansed with water and normal saline; three trials compared cleansing with no cleansing and one trial compared procaine spirit with water. There were no standard criteria for assessing wound infection across the trials, which limited the ability to pool the data. The major comparisons were water with normal saline, and tap water with no cleansing. For chronic wounds, the relative risk of developing an infection when cleansed with tap water compared with normal saline was 0.16, (95% CI 0.01 to 2.96). Tap water was more effective than saline in reducing the infection rate in adults with acute wounds (RR 0.63, 95% CI 0.40 to 0.99). The use of tap water to cleanse acute wounds in children was not associated with a statistically significant difference in infection when compared to saline (RR 1.07, 95% CI 0.43 to 2.64). We identified no statistically significant differences in infection rates when wounds were cleansed with tap water or not cleansed at all (RR 1.06, 95% CI 0.07 to 16.50). Likewise, there was no difference in the infection rate in episiotomy wounds cleansed with water or procaine spirit. The use of isotonic saline, distilled water and boiled water for cleansing open fractures also did not demonstrate a statistically significant difference in the number of fractures that were infected. AUTHORS'
conclusionsThere is no evidence that using tap water to cleanse acute wounds in adults increases infection and some evidence that it reduces it. However there is not strong evidence that cleansing wounds per se increases healing or reduces infection. In the absence of potable tap water, boiled and cooled water as well as distilled water can be used as wound cleansing agents.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.