Evidence map›Paper›PMID 22336796›Full record

SynthesisThe Cochrane database of systematic reviews2012

Water for wound cleansing.

Ritin Fernandez, Rhonda Griffiths

2 registry-linked trialsAbstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in The Cochrane database of systematic reviews, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 38 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 4 pooled it
20.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02714023 nacompletednot on this map

Water And Saline Head-to-head In The Blinded Evaluation Study Trial

TypeinterventionalSponsorUniversity of Missouri-ColumbiaRan2012 to 2017Enrolled241ConditionsAcute Appendicitis, AbscessArmsNormal Saline, Sterile Water
NCT02976480 narecruitingnot on this mapstarted 2017, after this paper: background citation

The Irrigation or No Irrigation in Simple Lacerations Trials

TypeinterventionalSponsorUniversité de SherbrookeRan2017 to 2025Enrolled1,000ConditionsLaceration - Injury, InfectionArmsIrrigation, No irrigation
3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 4 syntheses or guidelines pooled it, 237 citations in OpenAlex.

  1. Water for wound cleansing.The Cochrane database of systematic reviews · 2022
    Pooled it
  2. Pooled it
  3. Wound management in disaster settings.World journal of surgery · 2015
    Pooled it
  4. Wound cleansing for pressure ulcers.The Cochrane database of systematic reviews · 2013
    Pooled it
  5. Trial
  6. Article
  7. Review
  8. Review
  9. Article
  10. [Guidelines for neonatal skin management in the neonatal intensive care unit (2021)].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2021
    Article
  11. Article
  12. Article
  13. Simple Effective Ways to Care for Skin Wounds and Incisions.Plastic and reconstructive surgery. Global open · 2019
    Review
  14. Initial Assessment, Debridement, and Decision Making in the Salvage of Severely Injured Lower Extremity.Indian journal of plastic surgery : official publication of the Association of Plastic Surgeons of India · 2019
    Review
  15. Review
  16. [Primary soft tissue management in open fracture].Operative Orthopadie und Traumatologie · 2018
    Review
  17. Article
  18. Article
  19. Necrotizing fasciitis after scalpel injury sustained during postmortem examination.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2017
    Article
  20. Observational
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Ritin FernandezSchool of Nursing, Midwifery and Indigenous Health, University of Wollongong, Kogarah, Australia.ritin.fernandez@sesiahs.health.nsw.gov.au
Rhonda Griffiths
Sutherland Hospital · AUWestern Sydney University · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAlthough various solutions have been recommended for cleansing wounds, normal saline is favoured as it is an isotonic solution and does not interfere with the normal healing process. Tap water is commonly used in the community for cleansing wounds because it is easily accessible, efficient and cost effective; however, there is an unresolved debate about its use.

objectivesThe objective of this review was to assess the effects of water compared with other solutions for wound cleansing. SEARCH

methodsFor this fourth update we searched the Cochrane Wounds Group Specialised Register (searched 9 November 2011); The Cochrane Central Register of Controlled Trials (CENTRAL) (The Cochrane Library 2011, Issue 4); Ovid MEDLINE (2010 to October Week 4 2011); Ovid MEDLINE (In-Process & Other Non-Indexed Citations, November 8, 2011); Ovid EMBASE (2010 to 2011 Week 44); and EBSCO CINAHL (2010 to 4 November 2011). SELECTION CRITERIA: Randomised and quasi randomised controlled trials that compared the use of water with other solutions for wound cleansing were eligible for inclusion. Additional criteria were outcomes that included objective or subjective measures of wound infection or healing. DATA COLLECTION AND ANALYSIS: Two review authors independently carried out trial selection, data extraction and quality assessment. We settled differences in opinion by discussion. We pooled some data using a random-effects model. MAIN

resultsWe included 11 trials in this review. We identified seven trials that compared rates of infection and healing in wounds cleansed with water and normal saline; three trials compared cleansing with no cleansing and one trial compared procaine spirit with water. There were no standard criteria for assessing wound infection across the trials, which limited the ability to pool the data. The major comparisons were water with normal saline, and tap water with no cleansing. For chronic wounds, the relative risk of developing an infection when cleansed with tap water compared with normal saline was 0.16, (95% CI 0.01 to 2.96). Tap water was more effective than saline in reducing the infection rate in adults with acute wounds (RR 0.63, 95% CI 0.40 to 0.99). The use of tap water to cleanse acute wounds in children was not associated with a statistically significant difference in infection when compared to saline (RR 1.07, 95% CI 0.43 to 2.64). We identified no statistically significant differences in infection rates when wounds were cleansed with tap water or not cleansed at all (RR 1.06, 95% CI 0.07 to 16.50). Likewise, there was no difference in the infection rate in episiotomy wounds cleansed with water or procaine spirit. The use of isotonic saline, distilled water and boiled water for cleansing open fractures also did not demonstrate a statistically significant difference in the number of fractures that were infected. AUTHORS'

conclusionsThere is no evidence that using tap water to cleanse acute wounds in adults increases infection and some evidence that it reduces it. However there is not strong evidence that cleansing wounds per se increases healing or reduces infection. In the absence of potable tap water, boiled and cooled water as well as distilled water can be used as wound cleansing agents.

Indexed as

Drinking WaterHumansHydrotherapyRandomized Controlled Trials as TopicSkin UlcerSodium ChlorideTherapeutic IrrigationWound InfectionWounds and InjuriesDrinking WaterSodium Chloride

Identifiers

PMID22336796
OpenAlexW2017003391

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.