ReviewCurrent opinion in structural biology2012
Computational studies of molecular machines: the ribosome.
Review in Current opinion in structural biology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
27 citing papers in PubMed.
- Article
- Discovery of effectors for casein kinase signaling in the African trypanosome.Scientific reports · 2025Article
- Getting to the bottom of lncRNA mechanism: structure-function relationships.Mammalian genome : official journal of the International Mammalian Genome Society · 2022Review
- Arginine Methylation Regulates Ribosome CAR Function.International journal of molecular sciences · 2021Article
- Mechanism for the Unfolding of the TOP7 Protein in Steered Molecular Dynamics Simulations as Revealed by Mutual Information Analysis.Frontiers in molecular biosciences · 2021Article
- Modeling to Understand Plant Protein Structure-Function Relationships-Implications for Seed Storage Proteins.Molecules (Basel, Switzerland) · 2020Review
- RNA Structural Dynamics As Captured by Molecular Simulations: A Comprehensive Overview.Chemical reviews · 2018Review
- New tricks for old dogs: improving the accuracy of biomolecular force fields by pair-specific corrections to non-bonded interactions.Physical chemistry chemical physics : PCCP · 2018Review
- Solution structure of an ultra-stable single-chain insulin analog connects protein dynamics to a novel mechanism of receptor binding.The Journal of biological chemistry · 2018Article
- Stringent Nucleotide Recognition by the Ribosome at the Middle Codon Position.Molecules (Basel, Switzerland) · 2017Article
- Tracking fluctuation hotspots on the yeast ribosome through the elongation cycle.Nucleic acids research · 2017Article
- The fluctuating ribosome: thermal molecular dynamics characterized by neutron scattering.Scientific reports · 2016Article
- Centers of motion associated with EF-Tu binding to the ribosome.RNA biology · 2016Article
- Ribosome Mechanics Informs about Mechanism.Journal of molecular biology · 2016Review
- The ribosome's energy landscape: Recent insights from computation.Biophysical reviews · 2015Article
- GENESIS: a hybrid-parallel and multi-scale molecular dynamics simulator with enhanced sampling algorithms for biomolecular and cellular simulations.Wiley interdisciplinary reviews. Computational molecular science · 2015Article
- Major centers of motion in the large ribosomal RNAs.Nucleic acids research · 2015Article
- Structural Insights into tRNA Dynamics on the Ribosome.International journal of molecular sciences · 2015Review
- Molecular dynamics simulations of large macromolecular complexes.Current opinion in structural biology · 2015Review
- From static to dynamic: the need for structural ensembles and a predictive model of RNA folding and function.Current opinion in structural biology · 2015Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
Abstract
The past decade has produced an avalanche of experimental data on the structure and dynamics of the ribosome. Groundbreaking studies in structural biology and kinetics have placed important constraints on ribosome structural dynamics. However, a gulf remains between static structures and time dependent data. In particular, X-ray crystallography and cryo-EM studies produce static models of the ribosome in various states, but lack dynamic information. Single molecule studies produce information on the rates of transitions between these states but do not have high-resolution spatial information. Computational studies have aided in bridging this gap by providing atomic resolution simulations of structural fluctuations and transitions between configurations.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.