ArticleParasitology2012
Proteomic analysis of Plasmodium in the mosquito: progress and pitfalls.
Article in Parasitology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
21 citing papers in PubMed, 41 citations in OpenAlex.
- A 3D culture model facilitates mass production of in vitro Plasmodium falciparum haemolymph-like sporozoites.Malaria journal · 2025Article
- Functional characterization of a conserved membrane protein, Pbs54, involved in gamete fertilization in Plasmodium berghei.International journal for parasitology · 2024Article
- Evolutionary Insights into the Microneme-Secreted, Chitinase-Containing High-Molecular-Weight Protein Complexes Involved inInfection and immunity · 2022Article
- A conserved malaria parasite antigen Pb22 plays a critical role in male gametogenesis in Plasmodium berghei.Cellular microbiology · 2021Article
- Characterization of Cystoisospora suis sexual stages in vitro.Parasites & vectors · 2020Article
- Functional Characterization and Comparison ofMolecular & cellular proteomics : MCP · 2020Article
- Male-Specific Protein Disulphide Isomerase Function is Essential for Plasmodium Transmission and a Vulnerable Target for Intervention.Scientific reports · 2019Article
- Plasmodium Parasites Viewed through Proteomics.Trends in parasitology · 2018Review
- Characterization of Plasmodium berghei Pbg37 as Both a Pre- and Postfertilization Antigen with Transmission-Blocking Potential.Infection and immunity · 2018Article
- Transcriptome analysis based detection of Plasmodium falciparum development in Anopheles stephensi mosquitoes.Scientific reports · 2018Article
- Proteogenomic analysis of the total and surface-exposed proteomes of Plasmodium vivax salivary gland sporozoites.PLoS neglected tropical diseases · 2017Article
- Developing transmission-blocking strategies for malaria control.PLoS pathogens · 2017Review
- Ecological influences on the behaviour and fertility of malaria parasites.Malaria journal · 2016Article
- Interrogating the Plasmodium Sporozoite Surface: Identification of Surface-Exposed Proteins and Demonstration of Glycosylation on CSP and TRAP by Mass Spectrometry-Based Proteomics.PLoS pathogens · 2016Article
- The cell biology of malaria infection of mosquito: advances and opportunities.Cellular microbiology · 2015Review
- RNA Seq analysis of the Eimeria tenella gametocyte transcriptome reveals clues about the molecular basis for sexual reproduction and oocyst biogenesis.BMC genomics · 2015Article
- Differential roles of an Anopheline midgut GPI-anchored protein in mediating Plasmodium falciparum and Plasmodium vivax ookinete invasion.Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases · 2014Article
- High-speed holographic microscopy of malaria parasites reveals ambidextrous flagellar waveforms.Proceedings of the National Academy of Sciences of the United States of America · 2013Article
- Total and putative surface proteomics of malaria parasite salivary gland sporozoites.Molecular & cellular proteomics : MCP · 2013Article
- Changes in the transcriptome of the malaria parasite Plasmodium falciparum during the initial phase of transmission from the human to the mosquito.BMC genomics · 2013Article
Corrections and comments
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Authors and funding
11 authors at 4 institutions in 4 countries.
Funding
Abstract
Here we discuss proteomic analyses of whole cell preparations of the mosquito stages of malaria parasite development (i.e. gametocytes, microgamete, ookinete, oocyst and sporozoite) of Plasmodium berghei. We also include critiques of the proteomes of two cell fractions from the purified ookinete, namely the micronemes and cell surface. Whereas we summarise key biological interpretations of the data, we also try to identify key methodological constraints we have met, only some of which we were able to resolve. Recognising the need to translate the potential of current genome sequencing into functional understanding, we report our efforts to develop more powerful combinations of methods for the in silico prediction of protein function and location. We have applied this analysis to the proteome of the male gamete, a cell whose very simple structural organisation facilitated interpretation of data. Some of the in silico predictions made have now been supported by ongoing protein tagging and genetic knockout studies. We hope this discussion may assist future studies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.