ArticleThe journal of spinal cord medicine2012
Pituitary carcinoma recurrent to the lumbar intradural extramedullary space: case report.
Article in The journal of spinal cord medicine, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 20 citations in OpenAlex.
- Cervical vertebral body metastasis from a gonadotroph pituitary neuroendocrine tumor: illustrative case.Journal of neurosurgery. Case lessons · 2026Article
- Aggressive and malignant pituitary tumours: does the sex matter?Pituitary · 2026Review
- Clinical features of pituitary carcinoma: analysis based on a case report and literature review.Frontiers in endocrinology · 2024Review
- Benign pituitary adenoma with multiple intracranial metastases-a case report and review of the literature.Journal of surgical case reports · 2022Article
- Aggressive Cushing's Disease: Molecular Pathology and Its Therapeutic Approach.Frontiers in endocrinology · 2021Review
- Surgical treatment of aggressive pituitary adenomas and pituitary carcinomas.Reviews in endocrine & metabolic disorders · 2020Review
- Intradural extramedullary metastasis: a review of literature and case report.Spinal cord series and cases · 2019Review
- Corticotrophic pituitary carcinoma with cervical metastases: case series and literature review.Pituitary · 2018Review
- Pituitary carcinoma with intraspinal metastasis: report of two cases and review of the literature.International journal of clinical and experimental pathology · 2015Review
- Temozolomide Therapy for Aggressive Pituitary Tumors: Results in a Small Series of Patients from Argentina.International journal of endocrinology · 2015Article
- Pituitary carcinoma with fourth ventricle metastasis: treatment by excision and Gamma-knife radiosurgery.Pituitary · 2014Article
- Molecular status of pituitary carcinoma and atypical adenoma that contributes the effectiveness of temozolomide.Medical molecular morphology · 2014Review
- Treatment of pituitary carcinomas and atypical pituitary adenomas: a review.Neurologia medico-chirurgica · 2014Review
- Prolactin Secreting Pituitary Carcinoma with Extracranial Spread Presenting with Pathological Fracture of Femur.Journal of neurosciences in rural practiceArticle
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
contextPituitary tumors are rare, and pituitary carcinomas are rarer still. Prognosis is poor, with less than 50% of patients surviving past 1 year after diagnosis. In this case of spinal metastasis from an adrenocorticotropic hormone-secreting pituitary carcinoma, the intradural extramedullary metastases recurred in the same lumbar area 6 years apart.
findingsFourteen years prior to presentation in our clinic, a 48-year-old woman was diagnosed with pituitary adenoma which was treated with resection followed by radiation. Eight years later, an intradural extramedullary spinal drop metastasis at L2-L3 was again treated with resection and radiation. Three years later, magnetic resonance imaging (MRI) revealed a mass encasing the right carotid artery, which was treated for 1 year with chemotherapy using temozolomide (Temodar). Three years later, MRI showed intradural extramedullary metastases at the L3-L4 intervertebral disc space and behind the L3 vertebral body; treatment was again resection followed by radiation. Back pain and weakness resolved after surgery and her neurological examination returned to baseline. There was no evidence of recurrence 1 year after surgery. CONCLUSION/CLINICAL RELEVANCE: In this unusual case, this pituitary carcinoma metastasized twice in 6 years to virtually the same intradural extramedullary lumbar region. Surgical resection of these masses aided in relieving neurological symptoms and prolonging life.
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