SynthesisAIDS (London, England)2012
Social and structural factors associated with HIV disease progression among illicit drug users: a systematic review.
Synthesis in AIDS (London, England), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
54 citing papers in PubMed, 1 synthesis or guideline pooled it, 74 citations in OpenAlex.
- The paradigm of universal access to HIV-treatment and human rights violation: how do we treat HIV-positive people who use drugs?Current HIV/AIDS reports · 2014Pooled it
- Development of a Multi-Target Contingency Management Intervention for HIV Positive Substance Users.Journal of substance abuse treatment · 2017Trial
- Trial
- High prevalence of illicit drug use in men who have sex with men with HIV-1 infection in Japan.PloS one · 2013Trial
- Structural determinants and health-related quality of life among people living with HIV: a systematic review and meta-analysis protocol.Systematic reviews · 2026Article
- Article
- A spatially dynamic agent-based model for assessing the effect of gentrification-induced migration and HIV transmission among heterosexual African American/Black women.Annals of epidemiology · 2025Article
- Long-Term Health-Related Quality of Life in People Living with HIV Who Present to Care with AIDS or Severe Immunodeficiency: The CoRIS AIDS Survivors Study.AIDS and behavior · 2025Article
- Exploring HIV Risk Among Sexual Minority Women by Identity and Behavior in a Population-Based Sample of Low-Income Heterosexually Active Women.LGBT health · 2025Article
- Intersectional forces of urban inequality and the global HIV pandemic: a retrospective analysis.BMJ global health · 2025Review
- A retrospective study of tuberculosis prevalence and associated factors among HIV-positive key populations in Nigeria.PLOS global public health · 2024Article
- Perceptions of Long-Acting Injectable Antiretroviral Therapy Among People Living with HIV Who Use Drugs and Service Providers: a Qualitative Analysis in Rhode Island.Journal of urban health : bulletin of the New York Academy of Medicine · 2023Article
- Cognitive Health in Persons With Human Immunodeficiency Virus: The Impact of Early Treatment, Comorbidities, and Aging.The Journal of infectious diseases · 2023Article
- How food support improves mental health among people living with HIV: A qualitative study.PloS one · 2023Article
- Material Security Scale as a Measurement of Poverty among Key Populations At-Risk for HIV/AIDS in Malaysia: An Implication for People Who Use Drugs and Transgender People during the COVID-19 Pandemic.International journal of environmental research and public health · 2022Article
- HIV viral load suppression before and after COVID-19 in Kinshasa and Haut Katanga, Democratic Republic of the Congo.Southern African journal of HIV medicine · 2022Article
- Article
- HIV treatment outcomes among people who acquired HIV via injecting drug use in the Asia-Pacific region: a longitudinal cohort study.Journal of the International AIDS Society · 2021Observational
- Impact of Advanced HIV Disease on Quality of Life and Mortality in the Era of Combined Antiretroviral Treatment.Journal of clinical medicine · 2021Review
- A qualitative investigation of HIV treatment dispensing models and impacts on adherence among people living with HIV who use drugs.PloS one · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 4 institutions in 3 countries.
Funding
Abstract
objectiveTo systematically review factors associated with HIV disease progression among illicit drug users, focusing on exposures exogenous to individuals that likely shape access and adherence to HIV treatment.
designA systematic review of peer-reviewed English-language studies among HIV-seropositive illicit drug users with at least one of these endpoint of interest: a diagnosis of AIDS; death; changes/differences in CD4 cell counts; or changes/differences in plasma HIV-1 RNA levels.
methodsArticles were included if they reported factors associated with an outcome of interest among a group of illicit drug users. Studies were identified, screened and selected using systematic methods.
resultsOf 2668 studies matching the search criteria, 58 (2%) met the inclusion criteria, all but one from North America or western Europe. Overall, 41 (71%) studies contained significant individual-level clinical characteristics or behaviors (e.g. illicit drug use) associated with disease progression. Fifteen studies (26%) identified significant social, physical, economic or policy-level exposures, including incarceration, housing status or lack of legal income.
conclusionAlthough past studies demonstrate important environmental exposures that appear to shape access to care and subsequent disease progression, the limited literature to examine these factors demonstrates the need for future research to consider risk environment characteristics and the role they may play in shaping health outcomes from HIV infection among drug users through determining access and adherence to evidence-based care.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.