Evidence map›Paper›PMID 22332055›Full record

ReviewAdvances in nutrition (Bethesda, Md.)2011

Current knowledge and future research on infant feeding in the context of HIV: basic, clinical, behavioral, and programmatic perspectives.

Sera L Young, Mduduzi N N Mbuya, Caroline J Chantry, Eveline P Geubbels, Kiersten Israel-Ballard, Deborah Cohan, Stephen A Vosti, Michael C Latham

Open access · bronzeAbstract readReview
In one paragraph

Review in Advances in nutrition (Bethesda, Md.), 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 2 pooled it
4.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 2 syntheses or guidelines pooled it, 67 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Childbirth Care among SARS-CoV-2 Positive Women in Italy.International journal of environmental research and public health · 2021
    Article
  12. Article
  13. Observational
  14. Assessing Medical Neglect in HIV-Exposed or Infected Children.Journal of child & adolescent trauma · 2020
    Article
  15. Article
  16. Should Infants Be Separated from Mothers with COVID-19? First, Do No Harm.Breastfeeding medicine : the official journal of the Academy of Breastfeeding Medicine · 2020
    Article
  17. Article
  18. Article
  19. Observational
  20. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 8 institutions in 3 countries.

Sera L YoungDepartment of Obstetrics, Gynecology and Reproductive Sciences, University of California, San Francisco, CA 94110, USA. sly3@cornell.edu
Mduduzi N N Mbuya
Caroline J Chantry
Eveline P Geubbels
Kiersten Israel-Ballard
Deborah Cohan
Stephen A Vosti
Michael C Latham
Cornell University · USIfakara Health Institute · TZProgram for Appropriate Technology in Health · USReproductive Science Center · USUniversity of California, Davis · USUniversity of California Davis Medical Center · USUniversity of California, San Francisco · USZvitambo Institute for Maternal and Child Health Research · ZW

Funding

Reproductive Infectious Disease (RID) FellowshipT32AI065388 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI COHEN, CRAIG R · 2007 to 2011
$781k
NIAID NIH HHS 5T32AI065388-04NIAID NIH HHS T32 AI065388
6 · The paper itself

Abstract

In 2008, between 129,000 and 194,000 of the 430,000 pediatric HIV infections worldwide were attributable to breastfeeding. Yet in many settings, the health, economic, and social consequences of not breastfeeding would have dire consequences for many more children. In the first part of this review we provide an overview of current knowledge about infant feeding in the context of HIV. Namely, we describe the benefits and risks of breastmilk, the evolution of recommended infant feeding modalities in high-income and low-income countries in the last two decades, and contextualize the recently revised guidelines for infant feeding in the context of HIV current knowledge. In the second section, we suggest areas for future research on the postnatal prevention of mother-to-child transmission of HIV (PMTCT) in developing and industrialized countries. We suggest two shifts in perspective. The first is to evaluate PMTCT interventions more holistically, to include the psychosocial and economic consequences as well as the biomedical ones. The second shift in perspective should be one that contextualizes postnatal PMTCT efforts in the cascade of maternal health services. We conclude by discussing basic, clinical, behavioral, and programmatic research questions pertaining to a number of PMTCT efforts, including extended postnatal ARV prophylaxis, exclusive breastfeeding promotion, counseling, breast milk pasteurization, breast milk banking, novel techniques for making breast milk safer, and optimal breastfeeding practices. We believe the research efforts outlined here will maximize the number of healthy, thriving, HIV-free children around the world.

Indexed as

Milk, HumanBiomedical ResearchBreast FeedingGuidelines as TopicHIV InfectionsHumansIncomeInfantInfectious Disease Transmission, VerticalMaternal Health Services

Identifiers

PMID22332055
PMCPMC3090166
OpenAlexW2142408239

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.