Evidence map›Paper›PMID 22331975›Full record

ArticleClinical ophthalmology (Auckland, N.Z.)2012

Revisiting corneal topography for the diagnosis of keratoconus: use of Rabinowitz's KISA% index.

Mohammad Reza Sedghipour, Afshin Lotfi Sadigh, Behzad Fallahi Motlagh

Abstract read
In one paragraph

Article in Clinical ophthalmology (Auckland, N.Z.), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Artificial intelligence for detecting keratoconus.The Cochrane database of systematic reviews · 2023
    Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Comparison of machine learning-based algorithms using corneal asymmetry vs. single-metric parameters for keratoconus detection.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2023
    Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Early diagnosis of keratoconus: what difference is it making?The British journal of ophthalmology · 2014
    Article
  12. Use of the toric intraocular lens for keratoconus treatment.Acta informatica medica : AIM : journal of the Society for Medical Informatics of Bosnia & Herzegovina : casopis Drustva za medicinsku informatiku BiH · 2014
    Article
  13. Imaging modalities in keratoconus.Indian journal of ophthalmology · 2013
    Review
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Mohammad Reza SedghipourDepartment of Ophthalmology, Tabriz University of Medical Sciences, Tabriz, Iran.
Afshin Lotfi Sadigh
Behzad Fallahi Motlagh

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNumerous videokeratographic methods are used in the diagnosis of keratoconus. The purpose of this study was to compare the sensitivity and specificity of the KISA% index with the keratometry (K) value, inferior-superior (I-S) value, relative skewing of the steepest radial axes (SRAX), and keratometric astigmatism (AST) indices in 25 patients presenting with bilateral keratoconus.

methodsTwenty-five patients presenting with bilateral keratoconus were enrolled. Fifty eyes from 25 healthy individuals without corneal abnormalities were used as controls. The clinical diagnosis of keratoconus was made by observation of scissors reflex at retinoscopy and characteristic slit lamp findings. Corneal topographic analysis was performed in each eye to calculate the K value, I-S value, AST, and SRAX indices.

resultsThe keratoconus percentage index (KISA%) was significantly more sensitive and specific than the other indices examined. Furthermore, it was significantly better at predicting positive and negative results than the other indices included in the study.

conclusionThe current research suggests that KISA% could be used to detect/diagnose keratoconus but further studies are required to confirm the specificity and sensitivity of KISA% for the detection of early-stage disease and keratoconus suspects.

Indexed as

corneakeratoconusKISA% index

Identifiers

PMID22331975
PMCPMC3273406

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.