ArticleBMJ open2012
Occupational and leisure time physical activity: risk of all-cause mortality and myocardial infarction in the Copenhagen City Heart Study. A prospective cohort study.
Article in BMJ open, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 70 papers, 8 of them syntheses that pooled it.
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The trial behind it
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Who cites it
70 citing papers in PubMed, 8 syntheses or guidelines pooled it.
- Physical activity trajectories and accumulation over adulthood and their associations with all-cause and cause-specific mortality: a systematic review and meta-analysis.British journal of sports medicine · 2025Pooled it
- High occupational physical activity and its combined effect with leisure-time physical activity on cardiovascular disease and mortality: systematic reviews and meta-analyses.Occupational and environmental medicine · 2025Pooled it
- The influence of workplace stressors on the risk of cardiovascular diseases among healthcare providers: a systematic review.Frontiers in psychiatry · 2025Pooled it
- Perimenopausal Physical Activity and Dementia Risk: A Systematic Review.International journal of sports medicine · 2024Pooled it
- Leisure-time and occupational physical activity and risk of cardiovascular disease incidence: a systematic-review and dose-response meta-analysis of prospective cohort studies.The international journal of behavioral nutrition and physical activity · 2024Pooled it
- The effect of leisure time physical activity and sedentary behaviour on the health of workers with different occupational physical activity demands: a systematic review.The international journal of behavioral nutrition and physical activity · 2021Pooled it
- Occupational Physical Activity and Lung Cancer Risk: A Systematic Review and Meta-Analysis.Sports medicine (Auckland, N.Z.) · 2020Pooled it
- Sociodemographic inequities associated with participation in leisure-time physical activity in sub-Saharan Africa: an individual participant data meta-analysis.BMC public health · 2020Pooled it
- Trial
- Do South Korean adults have insufficient levels of physical activity? Domain patterns and associations with self-rated health.PloS one · 2026Article
- Changes in physical activity across retirement: a compositional data analysis approach in a Swedish cohort study.European review of aging and physical activity : official journal of the European Group for Research into Elderly and Physical Activity · 2025Article
- The leisure time and occupational physical activity paradox in persistent musculoskeletal pain.Scientific reports · 2025Article
- How Do Occupational Sedentary Behavior and Occupational Cognitive Complexity Relate to Cognitive Function? A Cross-Sectional Study.Health science reports · 2025Article
- Associations of psychosocial and physical work demands with all-cause mortality: a pooled analysis of prospective cohort studies.International journal of epidemiology · 2025Article
- Article
- Association of Occupational and Leisure-Time Physical Activity With Allostatic Load.American journal of preventive medicine · 2024Article
- Sex disparities in physical activity domains and hypertension prevalence.Clinical hypertension · 2024Article
- Article
- Physical workload and cardiopulmonary parameters in relation to individual capacity of bulk waste workers - a cross-sectional field-study.Journal of occupational medicine and toxicology (London, England) · 2023Article
- Associations of physical activity types and intensity with cardiovascular diseases by age and gender among 18,730 Chinese adults.Scientific reports · 2023Article
10 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesMen with low physical fitness and high occupational physical activity are recently shown to have an increased risk of cardiovascular disease and all-cause mortality. The association between occupational physical activity with cardiovascular disease and all-cause mortality may also depend on leisure time physical activity.
designA prospective cohort study.
settingThe Copenhagen City Heart Study.
participants7819 men and women aged 25-66 years without a history of cardiovascular disease who attended an initial examination in the Copenhagen City Heart Study in 1976-1978. OUTCOME MEASURES: Myocardial infarction and all-cause mortality. Occupational physical activity was defined by combining information from baseline (1976-1978) with reassessment in 1981-1983. Conventional risk factors were controlled for in Cox analyses.
resultsDuring the follow-up from 1976 to 1978 until 2010, 2888 subjects died of all-cause mortality and 787 had a first event of myocardial infarction. Overall, occupational physical activity predicted all-cause mortality and myocardial infarction in men but not in women (test for interaction p=0.02). High occupational physical activity was associated with an increased risk of all-cause mortality among men with low (HR 1.56; 95% CI 1.11 to 2.18) and moderate (HR 1.31; 95% CI 1.05 to 1.63) leisure time physical activity but not among men with high leisure time physical activity (HR 1.00; 95% CI 0.78 to 1.26) (test for interaction p=0.04). Similar but weaker tendencies were found for myocardial infarction. Among women, occupational physical activity was not associated with subsequent all-cause mortality or myocardial infarction.
conclusionsThe findings suggest that high occupational physical activity imposes harmful effects particularly among men with low levels of leisure time physical activity.
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Registered trials
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