ArticleJournal of the American Association for Laboratory Animal Science : JAALAS2011
Assessment of sterility in fluid bags maintained for chronic use.
Article in Journal of the American Association for Laboratory Animal Science : JAALAS, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed, 7 citations in OpenAlex.
- Sterility and Stability of Diluted Meloxicam in Compounded Multi-dose Vial after 365 Days.Journal of the American Association for Laboratory Animal Science : JAALAS · 2019Article
- Sterility and Stability of Diluted Carprofen in a Multidose Vial in the Laboratory Animal Setting.Journal of the American Association for Laboratory Animal Science : JAALAS · 2017Article
- Ideal time to replace isotonic crystalloid intravenous fluids and sets.Veterinary evidenceReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Fluid therapy is an integral component of standard supportive care in veterinary medicine and is often given subcutaneously for ease of administration. Multiple animals may be treated by using the same bag. These bags often are used repeatedly until they are empty or until a time specified by an IACUC or similar advisory group. This practice introduces the risk of contamination. Here we assessed the sterility of multiple-use fluid bags in the laboratory setting for a maximum of 60 d. Bags were manipulated to mimic infrequent and frequent use. Bacterial cultures of fluid and bag wall and assays for endotoxin and ATP activity were negative at all time points through 30 d. Two fluid samples yielded bacterial growth at 60 d, although all other tests were negative. These results suggest that fluid bags used chronically can be maintained in a sterile condition for a maximum of 30 d.
Indexed as
Identifiers
22330719PMC3189676W1915853875What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.