Evidence map›Paper›PMID 22330327›Full record

ArticleLipids in health and disease2012

Rice protein improves adiposity, body weight and reduces lipids level in rats through modification of triglyceride metabolism.

Lin Yang, Jia-Hou Chen, Jie Lv, Qiong Wu, Tong Xu, Hua Zhang, Qiao-Hong Liu, Hong-Kun Yang

Open access · goldAbstract read
In one paragraph

Article in Lipids in health and disease, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 54 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Lin YangDepartment of Food Science, School of Food Science and Engineering, Harbin Institute of Technology, 73 Huanghe Road, Harbin 150090, China. ly6617@hit.edu.cn
Jia-Hou Chen
Jie Lv
Qiong Wu
Tong Xu
Hua Zhang
Qiao-Hong Liu
Hong-Kun Yang
Harbin Institute of Technology · CNHeilongjiang Provincial Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo elucidate whether rice protein can possess a vital function in improving lipids level and adiposity, the effects of rice proteins extracted by alkaline (RP-A) and α-amylase (RP-E) on triglyceride metabolism were investigated in 7-week-old male Wistar rats fed cholesterol-enriched diets for 2 weeks, as compared with casein (CAS).

resultsCompared with CAS, plasma concentrations of glucose and lipids were significantly reduced by RP-feeding (P < 0.05), as well as hepatic accumulation of lipids (P < 0.05). RP-A and RP-E significantly depressed the hepatic activities of fatty acid synthase (FAS), glucose 6-phosphate dehydrogenase (G6PD) and malate dehydrogenase (MDH) (P < 0.05), whereas the activities of lipoprotein lipase (PL) and hepatic lipase (HL) were significantly stimulated (P < 0.05), as compared to CAS. Neither lipids level nor activities of enzymes were different between RP-A and RP-E (P > 0.05). There was a significant positive correlation between protein digestibility and deposit fat (r = 0.8567, P < 0.05), as well as the plasma TG concentration (r = 0.8627, P < 0.05).

conclusionsThe present study demonstrates that rice protein can modify triglyceride metabolism, leading to an improvement of body weight and adiposity. Results suggest that the triglyceride-lowering action as well as the potential of anti-adiposity induced by rice protein is attributed to upregulation of lipolysis and downregulation of lipogenesis, and the lower digestibility of rice protein may be the main modulator responsible for the lipid-lowering action.

Indexed as

AdiposityAlanine TransaminaseAmino AcidsAnimalsAnti-Obesity AgentsAspartate AminotransferasesDiet, High-FatFecesLipidsLipogenesisLipolysisLipotropic AgentsLiverMaleOryzaPlant ExtractsAlanine TransaminaseAmino AcidsAnti-Obesity AgentsAspartate AminotransferasesLipidsLipotropic AgentsPlant ExtractsPlant ProteinsTriglycerides

Identifiers

PMID22330327
PMCPMC3311603
OpenAlexW2145045539

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.