Cardiac safety, drug-induced QT prolongation and torsade de pointes (TdP).

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

12 citing papers in PubMed.

1. Human Cardiac Organoids: Advances and Prospects from Construction to Preclinical Drug Evaluation.Cells · 2025
   Review
2. GraphDeep-hERG: Graph Neural Network PharmacoAnalytics for Assessing hERG-Related Cardiotoxicity.Pharmaceutical research · 2025
   Article
3. Clomipramine potentially induced fatal torsades de pointes in a patient with acute decompensated heart failure: a case report.Frontiers in psychiatry · 2025
   Article
4. Cardiac Safety of Osimertinib: A Review of Data.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2021
   Review
5. Applications for Induced Pluripotent Stem Cells in Disease Modelling and Drug Development for Heart Diseases.European cardiology · 2020
   Review
6. Factors to Consider in the Selection of Dopamine Agonists for Older Persons with Parkinson's Disease.Drugs & aging · 2019
   Article
7. A meta-analysis on the cardiac safety profile of domperidone compared to metoclopramide.United European gastroenterology journal · 2018
   Article
8. Investigating the Additive Interaction of QT-Prolonging Drugs in Older People Using Claims Data.Drug safety · 2017
   Article
9. PCSK9 Inhibition With Monoclonal Antibodies: Modern Management of Hypercholesterolemia.Journal of clinical pharmacology · 2017
   Review
10. The role of concentration--effect relationships in the QTc interval prolongation: case sotalol.British journal of clinical pharmacology · 2015
    Article
11. Cardiovascular drug discovery: a perspective from a research-based pharmaceutical company.Cold Spring Harbor perspectives in medicine · 2014
    Review
12. Anesthesia in a patient with gitelman syndrome.Journal of anaesthesiology, clinical pharmacology
    Article

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

Authors and funding

1 author.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

Indexed as