ArticlePloS one2012
Canadian valuation of EQ-5D health states: preliminary value set and considerations for future valuation studies.
Article in PloS one, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05990166 (Randomised Controlled Trial to Assess the Effect of a Mineral-enriched Powder on Iron Deficiency in Women of Reproductive Age), which is not on this map. Cited by 125 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Randomised Controlled Trial to Assess the Effect of a Mineral-enriched Powder on Iron Deficiency in Women of Reproductive Age
Who cites it
125 citing papers in PubMed, 2 syntheses or guidelines pooled it.
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- Health state utility values measured using the EuroQol 5-dimensions questionnaire in adults with chronic hepatitis C: a systematic literature review and meta-analysis.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2019Pooled it
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- Economic Evaluation of Exercise or Cognitive and Social Enrichment Activities for Improved Cognition After Stroke.JAMA network open · 2023Trial
- Sensitivity to change of generic preference-based instruments (EQ-5D-3L, EQ-5D-5L, and HUI3) in the context of treatment for people with prescription-type opioid use disorder in Canada.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2023Trial
- Establishing the minimal clinically important difference of the EQ-5D-3L in older adults with a history of falls.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2022Trial
- A Prospective Economic Analysis of Early Outcome Data From the Alliance A041202/ CCTG CLC.2 Randomized Phase III Trial Of Bendamustine-Rituximab Compared With Ibrutinib-Based Regimens in Untreated Older Patients With Chronic Lymphocytic Leukemia.Clinical lymphoma, myeloma & leukemia · 2021Trial
- Early apixaban therapy after ischemic stroke in patients with atrial fibrillation.Journal of neurology · 2021Trial
- Convergent validity of the EQ-5D-3L in a randomized-controlled trial of the Housing First model.BMC health services research · 2019Trial
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- Evaluation of a community paramedicine health promotion and lifestyle risk assessment program for older adults who live in social housing: a cluster randomized trial.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2018Trial
- Economic evaluation of aerobic exercise training in older adults with vascular cognitive impairment: PROMoTE trial.BMJ open · 2017Trial
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- Cost-Effectiveness Analysis of High-Efficiency Hemodiafiltration Versus Low-Flux Hemodialysis Based on the Canadian Arm of the CONTRAST Study.Applied health economics and health policy · 2015Trial
- The added effect of comorbidity on health-related quality of life in patients with asthma.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2015Trial
- Expanding Paramedicine in the Community (EPIC): study protocol for a randomized controlled trial.Trials · 2014Trial
- Cost-effectiveness of compression technologies for evidence-informed leg ulcer care: results from the Canadian Bandaging Trial.BMC health services research · 2012Trial
65 more citing papers are in PubMed but not listed here.
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Authors and funding
4 authors.
Funding
Abstract
backgroundThe EQ-5D is a preference based instrument which provides a description of a respondent's health status, and an empirically derived value for that health state often from a representative sample of the general population. It is commonly used to derive Quality Adjusted Life Year calculations (QALY) in economic evaluations. However, values for health states have been found to differ between countries. The objective of this study was to develop a set of values for the EQ-5D health states for use in Canada.
methodsValues for 48 different EQ-5D health states were elicited using the Time Trade Off (TTO) via a web survey in English. A random effect model was fitted to the data to estimate values for all 243 health states of the EQ-5D. Various model specifications were explored. Comparisons with EQ-5D values from the UK and US were made. Sensitivity analysis explored different transformations of values worse than dead, and exclusion criteria of subjects.
resultsThe final model was estimated from the values of 1145 subjects with socio-demographics broadly representative of Canadian general population with the exception of Quebec. This yielded a good fit with observed TTO values, with an overall R2 of 0.403 and a mean absolute error of 0.044.
conclusionA preference-weight algorithm for Canadian studies that include the EQ-5D is developed. The primary limitations regarded the representativeness of the final sample, given the language used (English only), the method of recruitment, and the difficulty in the task. Insights into potential issues for conducting valuation studies in countries as large and diverse as Canada are gained.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.