ArticleArchives of medical science : AMS2011
Reduced coenzyme Q(10) in female smokers and its association with lipid profile in a young healthy adult population.
Article in Archives of medical science : AMS, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
7 citing papers in PubMed, 14 citations in OpenAlex.
- Coenzyme Q10 and Xenobiotic Metabolism: An Overview.International journal of molecular sciences · 2025Review
- The Association between the Atherogenic Index of Plasma and Cardiometabolic Risk Factors: A Review.Healthcare (Basel, Switzerland) · 2023Review
- Coenzyme QAmerican journal of translational research · 2021Article
- A Mitochondrial Specific Antioxidant Reverses Metabolic Dysfunction and Fatty Liver Induced by Maternal Cigarette Smoke in Mice.Nutrients · 2019Article
- MitoQ supplementation prevent long-term impact of maternal smoking on renal development, oxidative stress and mitochondrial density in male mice offspring.Scientific reports · 2018Article
- Smoking habits and coenzyme Q10 status in healthy European adults.Archives of medical science : AMS · 2016Article
- Metabolomics reveals effects of maternal smoking on endogenous metabolites from lipid metabolism in cord blood of newborns.Metabolomics : Official journal of the Metabolomic SocietyArticle
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionCigarette smoking has a negative effect on body reserve of antioxidants and cholesterol metabolism. Coenzyme Q(10) (CoQ(10)), a potent antioxidant synthesized as part of the cholesterol pathway, is a potential biomarker for systemic oxidative stress. We aimed to investigate gender variation in plasma lipid profile and CoQ(10) concentrations in healthy non-smokers and in smokers. MATERIAL AND
methodsThe study included 55 cigarette smokers (25 females and 30 males) and 51 non-smokers (25 females and 26 males) with the age range from 21 to 45 years, and who had no history of alcohol abuse or chronic diseases such as diabetes mellitus or obesity. Coenzyme Q(10) plasma concentrations were measured by reverse-phase high performance liquid chromatography (HPLC) with ultraviolet detection. Fasting plasma glucose and lipid levels were determined by standard colorimetric methods.
resultsOur results showed that CoQ(10) concentrations were significantly decreased in smokers, especially in females, than their non-smoker counterparts. Female smokers also exhibited a significant decrease in plasma concentrations of total cholesterol (TC), HDL-C, LDL-C, and atherogenic ratios HDL-C/TC and CoQ(10)/LDL-C than male counterparts. Plasma triglyceride concentrations were increased in smokers irrespective of gender. Plasma CoQ(10) was relatively more associated with TC and LDL-C in female smokers than male smokers.
conclusionsThe adverse effects of smoking on body reserve of antioxidants and cholesterol metabolism are greater in females than in males, partially as a result of decreased CoQ(10) plasma concentrations, HDL-C and total-cholesterol and abnormal atherogenicity indices.
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