ArticleProceedings of the National Academy of Sciences of the United States of America2012
Thioredoxin-insensitive plastid ATP synthase that performs moonlighting functions.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
18 citing papers in PubMed, 47 citations in OpenAlex.
- Paradoxical energetics in the polar diatom Fragilariopsis cylindrus exposed to extreme low light.Plant physiology · 2026Article
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- The chloroplast ATP synthase redox domain inProceedings of the National Academy of Sciences of the United States of America · 2024Article
- Chloroplast ATP synthase: From structure to engineering.The Plant cell · 2024Review
- High cyclic electron transfer via the PGR5 pathway in the absence of photosynthetic control.Plant physiology · 2023Article
- Characterization of mutants deficient in N-terminal phosphorylation of the chloroplast ATP synthase subunit β.Plant physiology · 2023Article
- FZL, a dynamin-like protein localized to curved grana edges, is required for efficient photosynthetic electron transfer inFrontiers in plant science · 2023Article
- Chloroplast protease/chaperone AtDeg2 holds γPhotosynthetica · 2022Article
- Caught in action: fine-scale plastome evolution in the parasitic plants of Cuscuta section Ceratophorae (Convolvulaceae).Plant molecular biology · 2019Article
- The Non-Mendelian Green Cotyledon Gene in Soybean Encodes a Small Subunit of Photosystem II.Plant physiology · 2017Article
- The Role of Light-Dark Regulation of the Chloroplast ATP Synthase.Frontiers in plant science · 2017Article
- Proteome Profiling of Paulownia Seedlings Infected with Phytoplasma.Frontiers in plant science · 2017Article
- Limitations to photosynthesis by proton motive force-induced photosystem II photodamage.eLife · 2016Article
- MultispeQ Beta: a tool for large-scale plant phenotyping connected to the open PhotosynQ network.Royal Society open science · 2016Article
- Respiratory processes in non-photosynthetic plastids.Frontiers in plant science · 2015Review
- The chloroplast ATP synthase features the characteristic redox regulation machinery.Antioxidants & redox signaling · 2013Review
- Light- and metabolism-related regulation of the chloroplast ATP synthase has distinct mechanisms and functions.The Journal of biological chemistry · 2013Article
Corrections and comments
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Authors and funding
7 authors at 5 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The chloroplast ATP synthase catalyzes the light-driven synthesis of ATP and acts as a key feedback regulatory component of photosynthesis. Arabidopsis possesses two homologues of the regulatory γ subunit of the ATP synthase, encoded by the ATPC1 and ATPC2 genes. Using a series of mutants, we show that both these subunits can support photosynthetic ATP synthesis in vivo with similar specific activities, but that in wild-type plants, only γ(1) is involved in ATP synthesis in photosynthesis. The γ(1)-containing ATP synthase shows classical light-induced redox regulation, whereas the mutant expressing only γ(2)-ATP synthase (gamma exchange-revised ATP synthase, gamera) shows equally high ATP synthase activity in the light and dark. In situ redox titrations demonstrate that the regulatory thiol groups on γ(2)-ATP synthase remain reduced under physiological conditions but can be oxidized by the strong oxidant diamide, implying that the redox potential for the thiol/disulphide transition in γ(2) is substantially higher than that for γ(1). This regulatory difference may be attributed to alterations in the residues near the redox-active thiols. We propose that γ(2)-ATP synthase functions to catalyze ATP hydrolysis-driven proton translocation in nonphotosynthetic plastids, maintaining a sufficient transthylakoid proton gradient to drive protein translocation or other processes. Consistent with this interpretation, ATPC2 is predominantly expressed in the root, whereas modifying its expression results in alteration of root hair development. Phylogenetic analysis suggests that γ(2) originated from ancient gene duplication, resulting in divergent evolution of functionally distinct ATP synthase complexes in dicots and mosses.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.