ArticleEuropean journal of clinical pharmacology2012
Treatment duration with selective serotonin reuptake inhibitors among children and adolescents in Finland: a nationwide register study.
Article in European journal of clinical pharmacology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed, 2 syntheses or guidelines pooled it, 10 citations in OpenAlex.
- Trends in age-sex-specific prevalence and incidence of antidepressant dispensation in the Nordic countries: a systematic review.British journal of clinical pharmacology · 2026Pooled it
- Psychotropic drug use among children and adolescents in the Nordic countries: a systematic review.European child & adolescent psychiatry · 2025Pooled it
- Persistence of antidepressant treatment in children and adolescents: A population-based cohort study.The Australian and New Zealand journal of psychiatry · 2026Article
- Treatment patterns of antidepressants in children and adolescents in Scandinavia.European child & adolescent psychiatry · 2025Article
- Medication management in the context of mental illness: an exploratory study of young people living in Australia.BMC public health · 2020Article
- Use of SSRIs among Danish children: a nationwide study.European child & adolescent psychiatry · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 6 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeWe assessed treatment duration with selective serotonin reuptake inhibitors (SSRIs) among children and adolescents and investigated the association between treatment duration, age, sex, active ingredient, season of initiation, and reimbursement rate.
methodData on reimbursed SSRIs dispensed to children and adolescents aged <18 years in noninstitutional settings in Finland from 1999 to 2005 were extracted from the National Prescription Register. The association between treatment duration and explanatory factors was analyzed using Cox proportional hazards models.
resultsSSRIs were reimbursed for 3,710 (35.8%) male and 6,666 female (64.2%) patients from 1999 to 2004, of whom 3,853 (37.1%) received ≤ 100 days' supply. Age ≤ 11 years [adjusted hazard ratio (HR) 0.87; 95% confidence interval (CI), 0.80-0.94] and 12-15 years (HR 0.89; 95% CI 0.84-0.93) was associated with longer treatment duration compared with adolescents aged 16-17 years. Shorter treatment duration was associated with initiating treatment from September to November compared with the other seasons. Recipients of a higher reimbursement rate had longer treatment duration (HR 0.46, 95% CI 0.39-0.55) compared with those who received a lower reimbursement rate. Shorter treatment duration was weakly associated with use of fluvoxamine (HR 1.16; 95% CI 1.03-1.30) compared with fluoxetine.
conclusionsShorter treatment duration was less common among younger children, when initiated from September to November and among recipients of a higher reimbursement rate.
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Registered trials
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