Evidence map›Paper›PMID 22327982›Full record

ArticleThe journal of trauma and acute care surgery2012

Theoretical increase of thyroid cancer induction from cervical spine multidetector computed tomography in pediatric trauma patients.

Ryan D Muchow, Kelly R Egan, Walter W Peppler, Paul A Anderson

Open access · greenAbstract read
In one paragraph

Article in The journal of trauma and acute care surgery, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
4.0field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.

  1. Risk of malignancy associated with head and neck CT in children: a systematic review.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2014
    Pooled it
  2. Observational
  3. CT scans to exclude spine fractures in children after negative radiographs may lead to increase in future cancer risk.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2019
    Article
  4. Observational
  5. Article
  6. Article
  7. Review
  8. Diagnosis of cervical spine injuries in children: a systematic review.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2013
    Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Ryan D MuchowDepartment of Orthopedic Surgery, University of Wisconsin-Madison, 1685 Highland Avenue, Madison, WI 53705, USA. rmuchow@uwhealth.org
Kelly R Egan
Walter W Peppler
Paul A Anderson
University of Wisconsin–Madison · US

Funding

INSTITUTIONAL CTSA (UW-MADISON): CLINICAL TRIALSUL1RR025011 · NCRR · UNIVERSITY OF WISCONSIN-MADISON · PI DREZNER, MARC KENNETH · 2007 to 2011
$29.5M
NCRR NIH HHS 1 UL1 RR025011NCRR NIH HHS UL1 RR025011
6 · The paper itself

Abstract

backgroundThe trend of increasing cervical spine multidirectional computed tomography (MDCT) imaging of pediatric trauma patients is characteristic of the overall dramatic increase in computed tomography utilization in the United States. The purpose of this study is to compare the amount of radiation a pediatric trauma patient absorbs to the thyroid from plain radiographs and MDCT of the cervical spine and to express risk by calculation of theoretical thyroid cancer induction.

methodsA retrospective evaluation of pediatric trauma patients admitted from October 1, 2004, to October 31, 2009, was performed at an academic, Level I trauma center. Inclusion criteria were Level I/II trauma patients, cervical spine imaging performed at our institution, and age <18 years. Absorbed thyroid radiation was calculated for patients receiving plain radiographs or MDCT. Thyroid cancer risk was calculated using the 2006 Biological Effects on Ionizing Radiation VII report.

resultsSix hundred seventeen patients met inclusion criteria: 224 received cervical spine radiographs and 393 received cervical spine MDCT. The mean thyroid radiation absorbed from radiographs was 0.90 mGy for males and 0.96 mGy for females compared with 63.6 mGy (males) and 64.2 mGy (females) receiving MDCT (p < 0.001). The median excess relative risk of thyroid cancer induction from one cervical spine MDCT in males was 13.0% and females was 25.0%, compared with 0.24% (males) and 0.51% (females) for radiographs (p < 0.001).

conclusionsThe significant difference in radiation that MDCT delivers to the pediatric trauma patient when compared with plain radiographs should temper routine use of computed tomography in pediatric cervical spine clearance algorithms.

Indexed as

AdolescentCervical VertebraeChildChild, PreschoolFemaleHumansInfantInfant, NewbornMaleNeoplasms, Radiation-InducedPrevalenceProspective StudiesRadiation DosageRadiometryRetrospective StudiesRisk Assessment

Identifiers

PMID22327982
PMCPMC4495661
OpenAlexW114887755

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.